Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7471.098 | 0.9254 | 0.9329 | 2.2704 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7471.098 | 1.0142 | 1.0125 | 2.2704 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7471.098 | 0.9562 | 0.9609 | 2.2704 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7471.098 | 0.9034 | 0.9125 | 2.2704 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7471.098 | 0.0337 | -0.5508 | 2.2704 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7471.098 | 0.4414 | 0.3951 | 2.2704 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7472.092 | 1.2356 | 1.3633 | 1.2676 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7472.092 | 1.1692 | 1.2625 | 1.2676 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7472.092 | 0.9616 | 0.9391 | 1.2676 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7472.092 | 1.5842 | 1.8752 | 1.2676 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7472.092 | 1.0817 | 1.1279 | 1.2676 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7472.092 | 1.3135 | 1.4800 | 1.2676 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7472.092 | 2.3185 | 2.8827 | 1.2676 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7472.092 | 0.2092 | -0.4180 | 1.2676 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7472.092 | 0.2222 | -0.3894 | 1.2676 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7472.098 | 1.4217 | 1.5249 | 1.5098 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7472.098 | 1.9696 | 2.1333 | 1.5098 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7472.098 | 2.0575 | 2.2253 | 1.5098 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7472.098 | 2.4965 | 2.6661 | 1.5098 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7472.098 | 1.0938 | 1.1224 | 1.5098 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7472.098 | 2.1938 | 2.3653 | 1.5098 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7472.098 | 2.0328 | 2.1996 | 1.5098 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7472.098 | 0.1871 | -0.3410 | 1.5098 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7472.098 | 0.1671 | -0.3886 | 1.5098 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000307 | uM | 7473.071 | 1.1821 | 1.1422 | 2.4352 |