Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7470.091 | 0.9981 | 0.9961 | 0.9773 | |
| HCC70 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7470.091 | 0.8582 | 0.7103 | 0.9773 | |
| HCC70 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7470.091 | 0.0091 | -0.9836 | 0.9773 | |
| HCC70 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 133 | uM | 7470.091 | 0.0116 | -0.9791 | 0.9773 | |
| HCC70 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7470.098 | 0.9941 | 0.9874 | 0.9387 | |
| HCC70 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7470.098 | 0.8983 | 0.7840 | 0.9387 | |
| HCC70 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7470.098 | 0.9366 | 0.8651 | 0.9387 | |
| HCC70 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7470.098 | 0.9553 | 0.9048 | 0.9387 | |
| HCC70 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7470.098 | 0.9636 | 0.9226 | 0.9387 | |
| HCC70 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7470.098 | 0.9154 | 0.8203 | 0.9387 | |
| HCC70 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7470.098 | 0.9363 | 0.8646 | 0.9387 | |
| HCC70 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7470.098 | 0.1290 | -0.7744 | 0.9387 | |
| HCC70 | TNBC | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7470.098 | 0.0158 | -0.9759 | 0.9387 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7471.092 | 0.5919 | -0.4858 | 0.3860 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7471.092 | 0.8425 | 0.2829 | 0.3860 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7471.092 | 1.1627 | 1.9552 | 0.3860 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7471.092 | 0.7392 | -0.0858 | 0.3860 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7471.092 | 0.9927 | 0.9626 | 0.3860 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7471.092 | 0.7425 | -0.0751 | 0.3860 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7471.092 | 0.4868 | -0.6901 | 0.3860 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7471.092 | 0.6056 | -0.4545 | 0.3860 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7471.092 | 0.0218 | -0.9999 | 0.3860 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7471.098 | 0.9437 | 0.9496 | 2.2704 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7471.098 | 0.9349 | 0.9415 | 2.2704 | |
| Hs 578T | TNBC | Basal B | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7471.098 | 0.9572 | 0.9618 | 2.2704 |