Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 1.07 | uM | 7456.091 | 0.9332 | 0.9231 | 1.7629 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 5.33 | uM | 7456.091 | 0.8397 | 0.8113 | 1.7629 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 26.7 | uM | 7456.091 | 0.0109 | -0.8458 | 1.7629 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 133 | uM | 7456.091 | 0.0106 | -0.8487 | 1.7629 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7456.098 | 0.9907 | 0.9893 | 1.7388 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7456.098 | 0.9314 | 0.9199 | 1.7388 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7456.098 | 0.9893 | 0.9877 | 1.7388 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7456.098 | 1.0023 | 1.0027 | 1.7388 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7456.098 | 1.0190 | 1.0217 | 1.7388 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7456.098 | 0.9815 | 0.9787 | 1.7388 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7456.098 | 0.9543 | 0.9469 | 1.7388 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7456.098 | 0.8301 | 0.7969 | 1.7388 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7456.098 | 0.9229 | 0.9098 | 1.7388 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.000171 | uM | 7457.07 | 0.9923 | 0.9902 | 1.5631 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.000853 | uM | 7457.07 | 0.9419 | 0.9249 | 1.5631 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.00427 | uM | 7457.07 | 1.0016 | 1.0020 | 1.5631 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.0213 | uM | 7457.07 | 0.9925 | 0.9904 | 1.5631 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.107 | uM | 7457.07 | 0.9698 | 0.9611 | 1.5631 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.533 | uM | 7457.07 | 0.9758 | 0.9689 | 1.5631 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 2.67 | uM | 7457.07 | 0.9055 | 0.8770 | 1.5631 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 13.3 | uM | 7457.07 | 0.3760 | 0.0697 | 1.5631 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 66.7 | uM | 7457.07 | 0.0307 | -0.7848 | 1.5631 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.000341 | uM | 7457.09 | 1.0385 | 1.0439 | 1.7392 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.00171 | uM | 7457.09 | 0.9611 | 0.9549 | 1.7392 | |
| HCC1954 | HER2amp | Basal A | GSK1838705A | IGF1R | RTK | 0.00853 | uM | 7457.09 | 0.9599 | 0.9535 | 1.7392 |