Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HBL-100 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.000427 | uM | 9226.001 | 0.9431 | 0.9564 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.00213 | uM | 9226.001 | 0.9455 | 0.9583 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.0107 | uM | 9226.001 | 0.7050 | 0.7534 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.0533 | uM | 9226.001 | 0.7315 | 0.7780 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK1070916 | AURK | AURK | 0.267 | uM | 9226.001 | 0.5816 | 0.6310 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK1070916 | AURK | AURK | 1.33 | uM | 9226.001 | 0.4529 | 0.4844 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK1070916 | AURK | AURK | 6.67 | uM | 9226.001 | 0.0639 | -0.2898 | 2.6569 | |
| HBL-100 | Unknown | Unknown | GSK1070916 | AURK | AURK | 33.3 | uM | 9226.001 | 0.0026 | -0.7877 | 2.6569 | |
| HCC1143 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0000853 | uM | 7810.001 | 0.8914 | 0.7618 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.000427 | uM | 7810.001 | 1.0228 | 1.0503 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.00213 | uM | 7810.001 | 1.0562 | 1.1244 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0107 | uM | 7810.001 | 0.9834 | 0.9633 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0533 | uM | 7810.001 | 0.8918 | 0.7626 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.267 | uM | 7810.001 | 0.8876 | 0.7535 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK1070916 | AURK | AURK | 1.33 | uM | 7810.001 | 0.8008 | 0.5652 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK1070916 | AURK | AURK | 6.67 | uM | 7810.001 | 0.6153 | 0.1702 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK1070916 | AURK | AURK | 33.3 | uM | 7810.001 | 0.0966 | -0.8483 | 0.9063 | |
| HCC1143 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0000853 | uM | 9233.001 | 0.9962 | 0.9922 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.000427 | uM | 9233.001 | 0.9797 | 0.9588 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.00213 | uM | 9233.001 | 1.0080 | 1.0164 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0107 | uM | 9233.001 | 0.9351 | 0.8681 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.0533 | uM | 9233.001 | 0.8954 | 0.7876 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK1070916 | AURK | AURK | 0.267 | uM | 9233.001 | 0.8677 | 0.7315 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK1070916 | AURK | AURK | 1.33 | uM | 9233.001 | 0.7995 | 0.5932 | 0.9839 | |
| HCC1143 | TNBC | Basal A | GSK1070916 | AURK | AURK | 6.67 | uM | 9233.001 | 0.6897 | 0.3710 | 0.9839 |