Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | GM6001 | MMP | MMP | 0.0107 | uM | 7468.096 | 0.9546 | 0.9417 | 1.5683 | |
| HCC38 | TNBC | Basal B | GM6001 | MMP | MMP | 0.0533 | uM | 7468.096 | 1.0005 | 1.0006 | 1.5683 | |
| HCC38 | TNBC | Basal B | GM6001 | MMP | MMP | 0.267 | uM | 7468.096 | 0.9474 | 0.9323 | 1.5683 | |
| HCC38 | TNBC | Basal B | GM6001 | MMP | MMP | 1.33 | uM | 7468.096 | 0.8833 | 0.8479 | 1.5683 | |
| HCC38 | TNBC | Basal B | GM6001 | MMP | MMP | 6.67 | uM | 7468.096 | 0.8987 | 0.8683 | 1.5683 | |
| HCC38 | TNBC | Basal B | GM6001 | MMP | MMP | 33.3 | uM | 7468.096 | 0.9675 | 0.9583 | 1.5683 | |
| HCC70 | TNBC | Basal A | GM6001 | MMP | MMP | 0.0000853 | uM | 7470.096 | 0.9705 | 0.9383 | 0.9576 | |
| HCC70 | TNBC | Basal A | GM6001 | MMP | MMP | 0.000427 | uM | 7470.096 | 0.9837 | 0.9661 | 0.9576 | |
| HCC70 | TNBC | Basal A | GM6001 | MMP | MMP | 0.00213 | uM | 7470.096 | 1.0081 | 1.0170 | 0.9576 | |
| HCC70 | TNBC | Basal A | GM6001 | MMP | MMP | 0.0107 | uM | 7470.096 | 1.0096 | 1.0202 | 0.9576 | |
| HCC70 | TNBC | Basal A | GM6001 | MMP | MMP | 0.0533 | uM | 7470.096 | 1.0133 | 1.0279 | 0.9576 | |
| HCC70 | TNBC | Basal A | GM6001 | MMP | MMP | 0.267 | uM | 7470.096 | 0.9046 | 0.8012 | 0.9576 | |
| HCC70 | TNBC | Basal A | GM6001 | MMP | MMP | 1.33 | uM | 7470.096 | 0.8400 | 0.6670 | 0.9576 | |
| HCC70 | TNBC | Basal A | GM6001 | MMP | MMP | 6.67 | uM | 7470.096 | 0.7523 | 0.4858 | 0.9576 | |
| HCC70 | TNBC | Basal A | GM6001 | MMP | MMP | 33.3 | uM | 7470.096 | 0.6336 | 0.2418 | 0.9576 | |
| MCF 10A | NM | Basal B | GM6001 | MMP | MMP | 0.0000853 | uM | 7485.096 | 0.9260 | 0.9580 | 3.6265 | |
| MCF 10A | NM | Basal B | GM6001 | MMP | MMP | 0.000427 | uM | 7485.096 | 0.9727 | 0.9848 | 3.6265 | |
| MCF 10A | NM | Basal B | GM6001 | MMP | MMP | 0.00213 | uM | 7485.096 | 0.9574 | 0.9762 | 3.6265 | |
| MCF 10A | NM | Basal B | GM6001 | MMP | MMP | 0.0107 | uM | 7485.096 | 1.0093 | 1.0051 | 3.6265 | |
| MCF 10A | NM | Basal B | GM6001 | MMP | MMP | 0.0533 | uM | 7485.096 | 0.8902 | 0.9369 | 3.6265 | |
| MCF 10A | NM | Basal B | GM6001 | MMP | MMP | 0.267 | uM | 7485.096 | 0.9569 | 0.9759 | 3.6265 | |
| MCF 10A | NM | Basal B | GM6001 | MMP | MMP | 1.33 | uM | 7485.096 | 0.8887 | 0.9360 | 3.6265 | |
| MCF 10A | NM | Basal B | GM6001 | MMP | MMP | 6.67 | uM | 7485.096 | 0.9034 | 0.9447 | 3.6265 | |
| MCF 10A | NM | Basal B | GM6001 | MMP | MMP | 33.3 | uM | 7485.096 | 0.8755 | 0.9280 | 3.6265 | |
| MCF12A | NM | Basal B | GM6001 | MMP | MMP | 0.0000853 | uM | 7490.096 | 0.9514 | 0.9617 | 2.5767 |