Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF12A | NM | Basal B | GM6001 | MMP | MMP | 0.000427 | uM | 7490.096 | 0.9833 | 0.9869 | 2.5767 | |
| MCF12A | NM | Basal B | GM6001 | MMP | MMP | 0.00213 | uM | 7490.096 | 0.9702 | 0.9767 | 2.5767 | |
| MCF12A | NM | Basal B | GM6001 | MMP | MMP | 0.0107 | uM | 7490.096 | 0.9776 | 0.9825 | 2.5767 | |
| MCF12A | NM | Basal B | GM6001 | MMP | MMP | 0.0533 | uM | 7490.096 | 1.0021 | 1.0016 | 2.5767 | |
| MCF12A | NM | Basal B | GM6001 | MMP | MMP | 0.267 | uM | 7490.096 | 0.9721 | 0.9781 | 2.5767 | |
| MCF12A | NM | Basal B | GM6001 | MMP | MMP | 1.33 | uM | 7490.096 | 0.9746 | 0.9802 | 2.5767 | |
| MCF12A | NM | Basal B | GM6001 | MMP | MMP | 6.67 | uM | 7490.096 | 0.9404 | 0.9529 | 2.5767 | |
| MCF12A | NM | Basal B | GM6001 | MMP | MMP | 33.3 | uM | 7490.096 | 0.9311 | 0.9454 | 2.5767 | |
| MCF7 | HR+ | Luminal | GM6001 | MMP | MMP | 0.0000853 | uM | 7493.096 | 0.9723 | 0.9524 | 1.1669 | |
| MCF7 | HR+ | Luminal | GM6001 | MMP | MMP | 0.000427 | uM | 7493.096 | 0.9742 | 0.9556 | 1.1669 | |
| MCF7 | HR+ | Luminal | GM6001 | MMP | MMP | 0.00213 | uM | 7493.096 | 0.9368 | 0.8911 | 1.1669 | |
| MCF7 | HR+ | Luminal | GM6001 | MMP | MMP | 0.0107 | uM | 7493.096 | 0.9910 | 0.9845 | 1.1669 | |
| MCF7 | HR+ | Luminal | GM6001 | MMP | MMP | 0.0533 | uM | 7493.096 | 1.0024 | 1.0041 | 1.1669 | |
| MCF7 | HR+ | Luminal | GM6001 | MMP | MMP | 0.267 | uM | 7493.096 | 0.9545 | 0.9217 | 1.1669 | |
| MCF7 | HR+ | Luminal | GM6001 | MMP | MMP | 1.33 | uM | 7493.096 | 0.9372 | 0.8918 | 1.1669 | |
| MCF7 | HR+ | Luminal | GM6001 | MMP | MMP | 6.67 | uM | 7493.096 | 0.9420 | 0.9002 | 1.1669 | |
| MCF7 | HR+ | Luminal | GM6001 | MMP | MMP | 33.3 | uM | 7493.096 | 0.9105 | 0.8456 | 1.1669 | |
| MDA-MB-157 | TNBC | Basal B | GM6001 | MMP | MMP | 0.0000853 | uM | 7496.096 | 0.9356 | 0.8801 | 1.0771 | |
| MDA-MB-157 | TNBC | Basal B | GM6001 | MMP | MMP | 0.000427 | uM | 7496.096 | 0.9208 | 0.8526 | 1.0771 | |
| MDA-MB-157 | TNBC | Basal B | GM6001 | MMP | MMP | 0.00213 | uM | 7496.096 | 0.9116 | 0.8352 | 1.0771 | |
| MDA-MB-157 | TNBC | Basal B | GM6001 | MMP | MMP | 0.0107 | uM | 7496.096 | 0.9911 | 0.9834 | 1.0771 | |
| MDA-MB-157 | TNBC | Basal B | GM6001 | MMP | MMP | 0.0533 | uM | 7496.096 | 0.9639 | 0.9328 | 1.0771 | |
| MDA-MB-157 | TNBC | Basal B | GM6001 | MMP | MMP | 0.267 | uM | 7496.096 | 0.9452 | 0.8980 | 1.0771 | |
| MDA-MB-157 | TNBC | Basal B | GM6001 | MMP | MMP | 1.33 | uM | 7496.096 | 0.9659 | 0.9366 | 1.0771 | |
| MDA-MB-157 | TNBC | Basal B | GM6001 | MMP | MMP | 6.67 | uM | 7496.096 | 0.9375 | 0.8836 | 1.0771 |