Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 10267.011 | 0.3472 | -0.8948 | 0.3592 | |
| UACC-812 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 10267.011 | 0.4018 | -0.8420 | 0.3592 | |
| UACC-812 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 10267.011 | 0.4017 | -0.8422 | 0.3592 | |
| UACC-812 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 144 | uM | 10267.011 | 0.3543 | -0.8887 | 0.3592 | |
| UACC-812 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0185 | uM | 10267.131 | 0.4521 | -0.7458 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0924 | uM | 10267.131 | 0.5568 | -0.5632 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.462 | uM | 10267.131 | 0.3916 | -0.8250 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 2.31 | uM | 10267.131 | 0.3627 | -0.8565 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 11.6 | uM | 10267.131 | 0.4126 | -0.7995 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 57.8 | uM | 10267.131 | 0.3675 | -0.8516 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 289 | uM | 10267.131 | 0.4029 | -0.8115 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 1440 | uM | 10267.131 | 0.4069 | -0.8066 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 7220 | uM | 10267.131 | 0.4773 | -0.7073 | 0.3849 | |
| UACC-893 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 9045.075 | 1.1635 | 1.4037 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00924 | uM | 9045.075 | 0.8775 | 0.7064 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.0462 | uM | 9045.075 | 1.2746 | 1.6853 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.231 | uM | 9045.075 | 1.0359 | 1.0875 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 1.16 | uM | 9045.075 | 0.9693 | 0.9256 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 5.78 | uM | 9045.075 | 0.8511 | 0.6445 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 28.9 | uM | 9045.075 | 1.0227 | 1.0552 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 144 | uM | 9045.075 | 1.2084 | 1.5168 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 722 | uM | 9045.075 | 0.9748 | 0.9389 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00037 | uM | 9953.011 | 1.1273 | 1.5812 | 0.4697 | |
| UACC-893 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00185 | uM | 9953.011 | 0.9355 | 0.7351 | 0.4697 | |
| UACC-893 | HER2amp | Luminal | Gemcitabine | DNA replication | DNA replication | 0.00925 | uM | 9953.011 | 1.1236 | 1.5632 | 0.4697 |