Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 9347.132 | 1.0187 | 1.0253 | 1.4716 | ||
| HCC1569 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 9347.132 | 0.9030 | 0.8660 | 1.4716 | ||
| HCC1569 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 9347.132 | 1.0670 | 1.0901 | 1.4716 | ||
| HCC1569 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 9347.132 | 0.9750 | 0.9658 | 1.4716 | ||
| HCC1806 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7829.016 | 1.0060 | 1.0061 | 1.9532 | ||
| HCC1806 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7829.016 | 1.0090 | 1.0092 | 1.9532 | ||
| HCC1806 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7829.016 | 1.0133 | 1.0136 | 1.9532 | ||
| HCC1806 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7829.016 | 0.9643 | 0.9631 | 1.9532 | ||
| HCC1806 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7829.016 | 1.0236 | 1.0240 | 1.9532 | ||
| HCC1806 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7829.016 | 1.0156 | 1.0159 | 1.9532 | ||
| HCC1806 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7829.016 | 0.9342 | 0.9315 | 1.9532 | ||
| HCC1806 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7829.016 | 0.0398 | -0.6163 | 1.9532 | ||
| HCC1806 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7829.016 | 0.0068 | -0.8442 | 1.9532 | ||
| HCC1806 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7830.016 | 0.9680 | 0.9682 | 2.0313 | ||
| HCC1806 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7830.016 | 0.8898 | 0.8883 | 2.0313 | ||
| HCC1806 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7830.016 | 0.9279 | 0.9277 | 2.0313 | ||
| HCC1806 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7830.016 | 0.8841 | 0.8823 | 2.0313 | ||
| HCC1806 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7830.016 | 0.9051 | 0.9042 | 2.0313 | ||
| HCC1806 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7830.016 | 0.8895 | 0.8880 | 2.0313 | ||
| HCC1806 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7830.016 | 0.8126 | 0.8057 | 2.0313 | ||
| HCC1806 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7830.016 | 0.3900 | 0.2581 | 2.0313 | ||
| HCC1806 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7830.016 | 0.8706 | 0.8681 | 2.0313 | ||
| HCC1937 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7832.016 | 1.0408 | 1.0645 | 1.2588 | ||
| HCC1937 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7832.016 | 0.9845 | 0.9753 | 1.2588 | ||
| HCC1937 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7832.016 | 1.0201 | 1.0318 | 1.2588 |