Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7832.016 | 1.0431 | 1.0682 | 1.2588 | ||
| HCC1937 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7832.016 | 1.0322 | 1.0511 | 1.2588 | ||
| HCC1937 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7832.016 | 0.9992 | 0.9987 | 1.2588 | ||
| HCC1937 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7832.016 | 1.0243 | 1.0385 | 1.2588 | ||
| HCC1937 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7832.016 | 0.9948 | 0.9918 | 1.2588 | ||
| HCC1937 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7832.016 | 0.7799 | 0.6416 | 1.2588 | ||
| HCC1937 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7834.016 | 0.9638 | 0.9643 | 2.0442 | ||
| HCC1937 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7834.016 | 0.9873 | 0.9876 | 2.0442 | ||
| HCC1937 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7834.016 | 1.0396 | 1.0384 | 2.0442 | ||
| HCC1937 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7834.016 | 0.9639 | 0.9643 | 2.0442 | ||
| HCC1937 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7834.016 | 0.9902 | 0.9904 | 2.0442 | ||
| HCC1937 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7834.016 | 0.9705 | 0.9709 | 2.0442 | ||
| HCC1937 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7834.016 | 0.9455 | 0.9460 | 2.0442 | ||
| HCC1937 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7834.016 | 0.9972 | 0.9972 | 2.0442 | ||
| HCC1937 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7834.016 | 0.8260 | 0.8214 | 2.0442 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7836.016 | 1.0311 | 1.0395 | 1.5669 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7836.016 | 1.0026 | 1.0033 | 1.5669 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7836.016 | 1.0268 | 1.0340 | 1.5669 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7836.016 | 0.9766 | 0.9700 | 1.5669 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7836.016 | 0.9811 | 0.9758 | 1.5669 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7836.016 | 0.8963 | 0.8650 | 1.5669 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7836.016 | 0.8521 | 0.8058 | 1.5669 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7836.016 | 0.6756 | 0.5572 | 1.5669 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7836.016 | 0.2960 | -0.0804 | 1.5669 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7837.016 | 1.0166 | 1.0183 | 1.8067 |