Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7837.016 | 0.8762 | 0.8589 | 1.8067 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7837.016 | 0.8900 | 0.8750 | 1.8067 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7837.016 | 0.8487 | 0.8264 | 1.8067 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7837.016 | 0.7965 | 0.7634 | 1.8067 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7837.016 | 0.7318 | 0.6825 | 1.8067 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7837.016 | 0.5933 | 0.4981 | 1.8067 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7837.016 | 0.7124 | 0.6578 | 1.8067 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7837.016 | 0.6437 | 0.5673 | 1.8067 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7839.016 | 1.2364 | 1.2924 | 1.5556 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7839.016 | 1.0314 | 1.0402 | 1.5556 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7839.016 | 1.2356 | 1.2913 | 1.5556 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7839.016 | 1.0874 | 1.1107 | 1.5556 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7839.016 | 1.1846 | 1.2301 | 1.5556 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7839.016 | 0.9984 | 0.9980 | 1.5556 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7839.016 | 0.9197 | 0.8953 | 1.5556 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7839.016 | 0.2924 | -0.0928 | 1.5556 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7839.016 | 0.7590 | 0.6751 | 1.5556 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 9386.132 | 1.0587 | 1.0826 | 1.4083 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 9386.132 | 0.9492 | 0.9273 | 1.4083 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 9386.132 | 0.8647 | 0.8038 | 1.4083 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 9386.132 | 1.0147 | 1.0209 | 1.4083 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 9386.132 | 1.0421 | 1.0595 | 1.4083 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 9386.132 | 1.0389 | 1.0550 | 1.4083 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 9386.132 | 0.8428 | 0.7712 | 1.4083 | ||
| HCC1954 | HER2amp | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 9386.132 | 0.9226 | 0.8888 | 1.4083 |