Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 10996.143 | 0.9653 | 0.7805 | 0.3034 | |
| HCC2185 | TNBC | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 10996.143 | 0.9844 | 0.8991 | 0.3034 | |
| HCC2185 | TNBC | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 10996.143 | 0.9665 | 0.7873 | 0.3034 | |
| HCC2185 | TNBC | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 10996.143 | 0.9658 | 0.7835 | 0.3034 | |
| HCC2185 | TNBC | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 10996.143 | 0.9331 | 0.5917 | 0.3034 | |
| HCC2185 | TNBC | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 10996.143 | 0.9440 | 0.6543 | 0.3034 | |
| HCC2185 | TNBC | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 10996.143 | 0.7662 | -0.1686 | 0.3034 | |
| HCC2185 | TNBC | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 10996.143 | 0.6140 | -0.5992 | 0.3034 | |
| HCC2185 | TNBC | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 12192.143 | 1.0741 | 1.2533 | 0.5995 | |
| HCC2185 | TNBC | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 12192.143 | 1.0153 | 1.0513 | 0.5995 | |
| HCC2185 | TNBC | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 12192.143 | 0.9969 | 0.9895 | 0.5995 | |
| HCC2185 | TNBC | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 12192.143 | 1.0440 | 1.1491 | 0.5995 | |
| HCC2185 | TNBC | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 12192.143 | 1.0255 | 1.0857 | 0.5995 | |
| HCC2185 | TNBC | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 12192.143 | 0.9255 | 0.7578 | 0.5995 | |
| HCC2185 | TNBC | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 12192.143 | 0.9731 | 0.9112 | 0.5995 | |
| HCC2185 | TNBC | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 12192.143 | 0.8507 | 0.5272 | 0.5995 | |
| HCC2185 | TNBC | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 12192.143 | 0.6400 | -0.0499 | 0.5995 | |
| HCC3153 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 10577.143 | 0.9573 | 0.9125 | 0.9750 | |
| HCC3153 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 0.064 | uM | 10577.143 | 0.9528 | 0.9032 | 0.9750 | |
| HCC3153 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 0.32 | uM | 10577.143 | 0.9305 | 0.8575 | 0.9750 | |
| HCC3153 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 1.6 | uM | 10577.143 | 0.9510 | 0.8995 | 0.9750 | |
| HCC3153 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 8 | uM | 10577.143 | 1.0196 | 1.0402 | 0.9750 | |
| HCC3153 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 40 | uM | 10577.143 | 0.9826 | 0.9643 | 0.9750 | |
| HCC3153 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 200 | uM | 10577.143 | 0.9523 | 0.9023 | 0.9750 | |
| HCC3153 | TNBC | Basal A | 5-DFUR | TYMS | TYMS | 1000 | uM | 10577.143 | 0.7722 | 0.5341 | 0.9750 |