Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 7849.04 | 0.5515 | -0.3291 | 0.5448 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 7849.04 | 0.3055 | -0.7732 | 0.5448 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 7849.04 | 0.3055 | -0.7732 | 0.5448 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 7849.04 | 0.2791 | -0.8078 | 0.5448 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 7849.04 | 0.2821 | -0.8041 | 0.5448 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 7849.04 | 0.2690 | -0.8205 | 0.5448 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9420.012 | 1.0342 | 1.2245 | 0.3162 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9420.012 | 0.9825 | 0.8912 | 0.3162 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9420.012 | 1.0269 | 1.1751 | 0.3162 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9420.012 | 0.4513 | -0.8384 | 0.3162 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9420.012 | 0.4274 | -0.8639 | 0.3162 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9420.012 | 0.4090 | -0.8816 | 0.3162 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9420.012 | 0.4195 | -0.8717 | 0.3162 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9420.012 | 0.3475 | -0.9293 | 0.3162 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9420.012 | 0.2799 | -0.9643 | 0.3162 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9421.012 | 0.9658 | 0.9049 | 0.7153 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9421.012 | 0.9676 | 0.9099 | 0.7153 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9421.012 | 0.9648 | 0.9022 | 0.7153 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9421.012 | 0.4675 | -0.3092 | 0.7153 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9421.012 | 0.4177 | -0.4098 | 0.7153 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9421.012 | 0.3897 | -0.4643 | 0.7153 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9421.012 | 0.3857 | -0.4721 | 0.7153 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9421.012 | 0.3630 | -0.5149 | 0.7153 | |
| HCC2185 | TNBC | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9421.012 | 0.2932 | -0.6402 | 0.7153 | |
| HCC3153 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 7853.04 | 0.9937 | 0.9923 | 1.6581 |