Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 7853.04 | 0.9955 | 0.9945 | 1.6581 | |
| HCC3153 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 7853.04 | 1.0136 | 1.0163 | 1.6581 | |
| HCC3153 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 7853.04 | 0.7690 | 0.7070 | 1.6581 | |
| HCC3153 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 7853.04 | 0.3180 | 0.0022 | 1.6581 | |
| HCC3153 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 7853.04 | 0.2525 | -0.1279 | 1.6581 | |
| HCC3153 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 4 | uM | 7853.04 | 0.2344 | -0.1663 | 1.6581 | |
| HCC3153 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 20 | uM | 7853.04 | 0.2470 | -0.1395 | 1.6581 | |
| HCC3153 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 100 | uM | 7853.04 | 0.2193 | -0.1990 | 1.6581 | |
| HCC3153 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 10056.012 | 0.9856 | 0.9697 | 0.9543 | |
| HCC3153 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 10056.012 | 0.9875 | 0.9738 | 0.9543 | |
| HCC3153 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 10056.012 | 1.0061 | 1.0128 | 0.9543 | |
| HCC3153 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 10056.012 | 0.9277 | 0.8487 | 0.9543 | |
| HCC3153 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 10056.012 | 0.5462 | 0.0612 | 0.9543 | |
| HCC3153 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 10056.012 | 0.3798 | -0.2748 | 0.9543 | |
| HCC3153 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 4 | uM | 10056.012 | 0.3699 | -0.2947 | 0.9543 | |
| HCC3153 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 20 | uM | 10056.012 | 0.3209 | -0.3922 | 0.9543 | |
| HCC3153 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 100 | uM | 10056.012 | 0.3127 | -0.4085 | 0.9543 | |
| HCC38 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9453.012 | 1.0210 | 1.0348 | 1.2055 | |
| HCC38 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9453.012 | 1.0211 | 1.0349 | 1.2055 | |
| HCC38 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9453.012 | 1.0044 | 1.0073 | 1.2055 | |
| HCC38 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9453.012 | 0.4390 | 0.0102 | 1.2055 | |
| HCC38 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9453.012 | 0.5342 | 0.1889 | 1.2055 | |
| HCC38 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9453.012 | 0.3345 | -0.1937 | 1.2055 | |
| HCC38 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9453.012 | 0.3207 | -0.2215 | 1.2055 | |
| HCC38 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9453.012 | 0.2408 | -0.3862 | 1.2055 |