Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9453.012 | 0.2304 | -0.4082 | 1.2055 | |
| HCC38 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9469.024 | 1.0637 | 1.1184 | 1.0746 | |
| HCC38 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9469.024 | 0.9747 | 0.9529 | 1.0746 | |
| HCC38 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9469.024 | 1.0543 | 1.1008 | 1.0746 | |
| HCC38 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9469.024 | 0.7217 | 0.4765 | 1.0746 | |
| HCC38 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9469.024 | 0.4445 | -0.0595 | 1.0746 | |
| HCC38 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9469.024 | 0.4624 | -0.0243 | 1.0746 | |
| HCC38 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9469.024 | 0.3504 | -0.2463 | 1.0746 | |
| HCC38 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9469.024 | 0.2946 | -0.3587 | 1.0746 | |
| HCC38 | TNBC | Basal B | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9469.024 | 0.3010 | -0.3457 | 1.0746 | |
| HCC70 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 7860.04 | 0.9989 | 0.9969 | 0.7003 | |
| HCC70 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 7860.04 | 1.0417 | 1.1202 | 0.7003 | |
| HCC70 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 7860.04 | 1.0384 | 1.1105 | 0.7003 | |
| HCC70 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 7860.04 | 1.0634 | 1.1836 | 0.7003 | |
| HCC70 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 7860.04 | 0.6237 | 0.0191 | 0.7003 | |
| HCC70 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 7860.04 | 0.3986 | -0.4622 | 0.7003 | |
| HCC70 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 4 | uM | 7860.04 | 0.3855 | -0.4872 | 0.7003 | |
| HCC70 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 20 | uM | 7860.04 | 0.3380 | -0.5750 | 0.7003 | |
| HCC70 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 100 | uM | 7860.04 | 0.3095 | -0.6253 | 0.7003 | |
| HCC70 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9501.024 | 0.9135 | 0.8123 | 0.9185 | |
| HCC70 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9501.024 | 1.0661 | 1.1444 | 0.9185 | |
| HCC70 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9501.024 | 1.0235 | 1.0513 | 0.9185 | |
| HCC70 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9501.024 | 0.8333 | 0.6398 | 0.9185 | |
| HCC70 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9501.024 | 0.3517 | -0.3588 | 0.9185 | |
| HCC70 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9501.024 | 0.2994 | -0.4619 | 0.9185 |