Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9210.024 | 0.7241 | 0.3797 | 0.8697 | |
| CAMA-1 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9210.024 | 0.6099 | 0.1326 | 0.8697 | |
| CAMA-1 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9210.024 | 0.5624 | 0.0318 | 0.8697 | |
| CAMA-1 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9210.024 | 0.5361 | -0.0235 | 0.8697 | |
| CAMA-1 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9210.024 | 0.4971 | -0.1046 | 0.8697 | |
| CAMA-1 | HR+ | Luminal | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9210.024 | 0.4664 | -0.1680 | 0.8697 | |
| HBL-100 | Unknown | Unknown | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 7807.04 | 1.0103 | 1.0096 | 2.1435 | |
| HBL-100 | Unknown | Unknown | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 7807.04 | 1.0216 | 1.0200 | 2.1435 | |
| HBL-100 | Unknown | Unknown | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 7807.04 | 0.9954 | 0.9957 | 2.1435 | |
| HBL-100 | Unknown | Unknown | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 7807.04 | 0.5552 | 0.5199 | 2.1435 | |
| HBL-100 | Unknown | Unknown | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 7807.04 | 0.1947 | -0.0679 | 2.1435 | |
| HBL-100 | Unknown | Unknown | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 7807.04 | 0.1442 | -0.1897 | 2.1435 | |
| HBL-100 | Unknown | Unknown | Geldanamycin | HSP90 | HSP90 | 4 | uM | 7807.04 | 0.1553 | -0.1610 | 2.1435 | |
| HBL-100 | Unknown | Unknown | Geldanamycin | HSP90 | HSP90 | 20 | uM | 7807.04 | 0.0838 | -0.3708 | 2.1435 | |
| HBL-100 | Unknown | Unknown | Geldanamycin | HSP90 | HSP90 | 100 | uM | 7807.04 | 0.0937 | -0.3372 | 2.1435 | |
| HBL-100 | Unknown | Unknown | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 9226.012 | 0.9811 | 0.9848 | 2.5039 | |
| HBL-100 | Unknown | Unknown | Geldanamycin | HSP90 | HSP90 | 0.00128 | uM | 9226.012 | 0.9884 | 0.9907 | 2.5039 | |
| HBL-100 | Unknown | Unknown | Geldanamycin | HSP90 | HSP90 | 0.0064 | uM | 9226.012 | 0.9565 | 0.9648 | 2.5039 | |
| HBL-100 | Unknown | Unknown | Geldanamycin | HSP90 | HSP90 | 0.032 | uM | 9226.012 | 0.3288 | 0.2826 | 2.5039 | |
| HBL-100 | Unknown | Unknown | Geldanamycin | HSP90 | HSP90 | 0.16 | uM | 9226.012 | 0.2097 | 0.0718 | 2.5039 | |
| HBL-100 | Unknown | Unknown | Geldanamycin | HSP90 | HSP90 | 0.8 | uM | 9226.012 | 0.1666 | -0.0224 | 2.5039 | |
| HBL-100 | Unknown | Unknown | Geldanamycin | HSP90 | HSP90 | 4 | uM | 9226.012 | 0.1293 | -0.1165 | 2.5039 | |
| HBL-100 | Unknown | Unknown | Geldanamycin | HSP90 | HSP90 | 20 | uM | 9226.012 | 0.1047 | -0.1880 | 2.5039 | |
| HBL-100 | Unknown | Unknown | Geldanamycin | HSP90 | HSP90 | 100 | uM | 9226.012 | 0.0683 | -0.3154 | 2.5039 | |
| HCC1143 | TNBC | Basal A | Geldanamycin | HSP90 | HSP90 | 0.000256 | uM | 7810.012 | 1.0206 | 1.0443 | 0.9298 |