Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 8 | uM | 10694.143 | 0.9272 | 0.9332 | 2.2259 | |
| Hs 578T | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 40 | uM | 10694.143 | 0.8695 | 0.8783 | 2.2259 | |
| Hs 578T | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 200 | uM | 10694.143 | 0.6369 | 0.6330 | 2.2259 | |
| Hs 578T | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 1000 | uM | 10694.143 | 0.4245 | 0.3609 | 2.2259 | |
| Hs 578T | TNBC | Basal B | 5-DFUR | TYMS | TYMS | 5000 | uM | 10694.143 | 0.2323 | 0.0380 | 2.2259 | |
| LY2 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 10816.143 | 0.9540 | 0.8193 | 0.4975 | |
| LY2 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 10816.143 | 1.0381 | 1.1560 | 0.4975 | |
| LY2 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 10816.143 | 1.1210 | 1.5160 | 0.4975 | |
| LY2 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 10816.143 | 1.0758 | 1.3165 | 0.4975 | |
| LY2 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 10816.143 | 0.8723 | 0.5197 | 0.4975 | |
| LY2 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 10816.143 | 0.3610 | -0.7420 | 0.4975 | |
| LY2 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 10816.143 | 0.2745 | -0.8513 | 0.4975 | |
| LY2 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 10816.143 | 0.1823 | -0.9347 | 0.4975 | |
| LY2 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 10816.143 | 0.0740 | -0.9893 | 0.4975 | |
| LY2 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 12319.143 | 1.2005 | 1.8464 | 0.5178 | |
| LY2 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 12319.143 | 0.7885 | 0.2638 | 0.5178 | |
| LY2 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 12319.143 | 1.0327 | 1.1281 | 0.5178 | |
| LY2 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 12319.143 | 0.6802 | -0.0498 | 0.5178 | |
| LY2 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 12319.143 | 0.6870 | -0.0315 | 0.5178 | |
| LY2 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 12319.143 | 0.4378 | -0.5943 | 0.5178 | |
| LY2 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 12319.143 | 0.3121 | -0.7890 | 0.5178 | |
| LY2 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 12319.143 | 0.1926 | -0.9169 | 0.5178 | |
| LY2 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 12319.143 | 0.0725 | -0.9874 | 0.5178 | |
| MB 157 | Unknown | Unknown | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 12580.143 | 0.9886 | 0.9898 | 2.2318 | |
| MB 157 | Unknown | Unknown | 5-DFUR | TYMS | TYMS | 0.064 | uM | 12580.143 | 0.9949 | 0.9954 | 2.2318 |