Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MB 157 | Unknown | Unknown | 5-DFUR | TYMS | TYMS | 0.32 | uM | 12580.143 | 1.0171 | 1.0152 | 2.2318 | |
| MB 157 | Unknown | Unknown | 5-DFUR | TYMS | TYMS | 1.6 | uM | 12580.143 | 1.0045 | 1.0041 | 2.2318 | |
| MB 157 | Unknown | Unknown | 5-DFUR | TYMS | TYMS | 8 | uM | 12580.143 | 0.6598 | 0.6600 | 2.2318 | |
| MB 157 | Unknown | Unknown | 5-DFUR | TYMS | TYMS | 40 | uM | 12580.143 | 0.3449 | 0.2413 | 2.2318 | |
| MB 157 | Unknown | Unknown | 5-DFUR | TYMS | TYMS | 200 | uM | 12580.143 | 0.3956 | 0.3200 | 2.2318 | |
| MB 157 | Unknown | Unknown | 5-DFUR | TYMS | TYMS | 1000 | uM | 12580.143 | 0.3640 | 0.2717 | 2.2318 | |
| MB 157 | Unknown | Unknown | 5-DFUR | TYMS | TYMS | 5000 | uM | 12580.143 | 0.2555 | 0.0852 | 2.2318 | |
| MCF 10A | NM | Basal B | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 11056.143 | 0.9362 | 0.9544 | 2.8628 | |
| MCF 10A | NM | Basal B | 5-DFUR | TYMS | TYMS | 0.064 | uM | 11056.143 | 1.0832 | 1.0566 | 2.8628 | |
| MCF 10A | NM | Basal B | 5-DFUR | TYMS | TYMS | 0.32 | uM | 11056.143 | 1.0435 | 1.0300 | 2.8628 | |
| MCF 10A | NM | Basal B | 5-DFUR | TYMS | TYMS | 1.6 | uM | 11056.143 | 0.9950 | 0.9965 | 2.8628 | |
| MCF 10A | NM | Basal B | 5-DFUR | TYMS | TYMS | 8 | uM | 11056.143 | 0.6691 | 0.7381 | 2.8628 | |
| MCF 10A | NM | Basal B | 5-DFUR | TYMS | TYMS | 40 | uM | 11056.143 | 0.2657 | 0.2589 | 2.8628 | |
| MCF 10A | NM | Basal B | 5-DFUR | TYMS | TYMS | 200 | uM | 11056.143 | 0.1861 | 0.1116 | 2.8628 | |
| MCF 10A | NM | Basal B | 5-DFUR | TYMS | TYMS | 1000 | uM | 11056.143 | 0.0457 | -0.3193 | 2.8628 | |
| MCF 10A | NM | Basal B | 5-DFUR | TYMS | TYMS | 5000 | uM | 11056.143 | 0.0067 | -0.6519 | 2.8628 | |
| MCF 10F | NM | - | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 12254.143 | 0.9723 | 0.9606 | 1.4110 | |
| MCF 10F | NM | - | 5-DFUR | TYMS | TYMS | 0.064 | uM | 12254.143 | 1.0501 | 1.0706 | 1.4110 | |
| MCF 10F | NM | - | 5-DFUR | TYMS | TYMS | 0.32 | uM | 12254.143 | 0.9695 | 0.9566 | 1.4110 | |
| MCF 10F | NM | - | 5-DFUR | TYMS | TYMS | 1.6 | uM | 12254.143 | 0.8843 | 0.8330 | 1.4110 | |
| MCF 10F | NM | - | 5-DFUR | TYMS | TYMS | 8 | uM | 12254.143 | 0.7539 | 0.6371 | 1.4110 | |
| MCF 10F | NM | - | 5-DFUR | TYMS | TYMS | 40 | uM | 12254.143 | 0.6902 | 0.5377 | 1.4110 | |
| MCF 10F | NM | - | 5-DFUR | TYMS | TYMS | 200 | uM | 12254.143 | 0.5751 | 0.3513 | 1.4110 | |
| MCF 10F | NM | - | 5-DFUR | TYMS | TYMS | 1000 | uM | 12254.143 | 0.4561 | 0.1466 | 1.4110 | |
| MCF 10F | NM | - | 5-DFUR | TYMS | TYMS | 5000 | uM | 12254.143 | 0.2867 | -0.1749 | 1.4110 |