Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 12056.143 | 0.7824 | 0.5676 | 1.0075 | |
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 12056.143 | 0.7185 | 0.4405 | 1.0075 | |
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 12056.143 | 0.5158 | 0.0366 | 1.0075 | |
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 12178.143 | 1.0111 | 1.0291 | 0.7617 | |
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 12178.143 | 0.9446 | 0.8558 | 0.7617 | |
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 12178.143 | 0.9581 | 0.8908 | 0.7617 | |
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 12178.143 | 0.9874 | 0.9671 | 0.7617 | |
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 12178.143 | 1.0549 | 1.1453 | 0.7617 | |
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 12178.143 | 0.9489 | 0.8669 | 0.7617 | |
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 12178.143 | 0.9489 | 0.8670 | 0.7617 | |
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 12178.143 | 0.7990 | 0.4896 | 0.7617 | |
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 12178.143 | 0.7112 | 0.2785 | 0.7617 | |
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 12291.143 | 0.9809 | 0.9326 | 0.5621 | |
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 12291.143 | 0.9864 | 0.9518 | 0.5621 | |
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 12291.143 | 0.9977 | 0.9919 | 0.5621 | |
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 12291.143 | 0.9259 | 0.7441 | 0.5621 | |
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 12291.143 | 1.0228 | 1.0818 | 0.5621 | |
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 12291.143 | 0.9130 | 0.7008 | 0.5621 | |
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 12291.143 | 0.8993 | 0.6559 | 0.5621 | |
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 12291.143 | 0.7214 | 0.1186 | 0.5621 | |
| BT-474 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 12291.143 | 0.5755 | -0.2515 | 0.5621 | |
| BT-483 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 10696.143 | 0.9821 | 0.9317 | 0.5188 | |
| BT-483 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 10696.143 | 1.0036 | 1.0141 | 0.5188 | |
| BT-483 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 10696.143 | 0.9459 | 0.7968 | 0.5188 | |
| BT-483 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 10696.143 | 0.9915 | 0.9673 | 0.5188 |