Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MB 157 | Unknown | Unknown | FR180204 | ERK1/2 | MAPK | 0.000256 | uM | 12580.166 | 1.0269 | 1.0286 | 1.8686 | |
| MB 157 | Unknown | Unknown | FR180204 | ERK1/2 | MAPK | 0.00128 | uM | 12580.166 | 1.0535 | 1.0565 | 1.8686 | |
| MB 157 | Unknown | Unknown | FR180204 | ERK1/2 | MAPK | 0.0064 | uM | 12580.166 | 1.0312 | 1.0331 | 1.8686 | |
| MB 157 | Unknown | Unknown | FR180204 | ERK1/2 | MAPK | 0.032 | uM | 12580.166 | 1.0552 | 1.0584 | 1.8686 | |
| MB 157 | Unknown | Unknown | FR180204 | ERK1/2 | MAPK | 0.16 | uM | 12580.166 | 1.0485 | 1.0514 | 1.8686 | |
| MB 157 | Unknown | Unknown | FR180204 | ERK1/2 | MAPK | 0.8 | uM | 12580.166 | 1.0670 | 1.0707 | 1.8686 | |
| MB 157 | Unknown | Unknown | FR180204 | ERK1/2 | MAPK | 4 | uM | 12580.166 | 0.9819 | 0.9805 | 1.8686 | |
| MB 157 | Unknown | Unknown | FR180204 | ERK1/2 | MAPK | 20 | uM | 12580.166 | 0.7345 | 0.6955 | 1.8686 | |
| MB 157 | Unknown | Unknown | FR180204 | ERK1/2 | MAPK | 100 | uM | 12580.166 | 0.5282 | 0.4213 | 1.8686 | |
| MCF 10A | NM | Basal B | FR180204 | ERK1/2 | MAPK | 0.0000853 | uM | 11056.149 | 0.9658 | 0.9763 | 2.9204 | |
| MCF 10A | NM | Basal B | FR180204 | ERK1/2 | MAPK | 0.000427 | uM | 11056.149 | 1.0651 | 1.0436 | 2.9204 | |
| MCF 10A | NM | Basal B | FR180204 | ERK1/2 | MAPK | 0.00213 | uM | 11056.149 | 1.0129 | 1.0088 | 2.9204 | |
| MCF 10A | NM | Basal B | FR180204 | ERK1/2 | MAPK | 0.0107 | uM | 11056.149 | 0.9372 | 0.9561 | 2.9204 | |
| MCF 10A | NM | Basal B | FR180204 | ERK1/2 | MAPK | 0.0533 | uM | 11056.149 | 0.9577 | 0.9707 | 2.9204 | |
| MCF 10A | NM | Basal B | FR180204 | ERK1/2 | MAPK | 0.267 | uM | 11056.149 | 0.9261 | 0.9481 | 2.9204 | |
| MCF 10A | NM | Basal B | FR180204 | ERK1/2 | MAPK | 1.33 | uM | 11056.149 | 1.0353 | 1.0239 | 2.9204 | |
| MCF 10A | NM | Basal B | FR180204 | ERK1/2 | MAPK | 6.67 | uM | 11056.149 | 1.0478 | 1.0322 | 2.9204 | |
| MCF 10A | NM | Basal B | FR180204 | ERK1/2 | MAPK | 33.3 | uM | 11056.149 | 0.8165 | 0.8659 | 2.9204 | |
| MCF 10F | NM | - | FR180204 | ERK1/2 | MAPK | 0.000256 | uM | 12254.161 | 0.9657 | 0.9507 | 1.3991 | |
| MCF 10F | NM | - | FR180204 | ERK1/2 | MAPK | 0.00128 | uM | 12254.161 | 1.0539 | 1.0765 | 1.3991 | |
| MCF 10F | NM | - | FR180204 | ERK1/2 | MAPK | 0.0064 | uM | 12254.161 | 1.0066 | 1.0095 | 1.3991 | |
| MCF 10F | NM | - | FR180204 | ERK1/2 | MAPK | 0.032 | uM | 12254.161 | 1.0052 | 1.0074 | 1.3991 | |
| MCF 10F | NM | - | FR180204 | ERK1/2 | MAPK | 0.16 | uM | 12254.161 | 1.0304 | 1.0432 | 1.3991 | |
| MCF 10F | NM | - | FR180204 | ERK1/2 | MAPK | 0.8 | uM | 12254.161 | 1.0805 | 1.1138 | 1.3991 | |
| MCF 10F | NM | - | FR180204 | ERK1/2 | MAPK | 4 | uM | 12254.161 | 1.3524 | 1.4816 | 1.3991 |