Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
Hs 578T
TNBC
Basal B
 FR180204
ERK1/2
MAPK
0.00213
uM
10694.149
 1.0380 1.0319 2.3563
Hs 578T
TNBC
Basal B
 FR180204
ERK1/2
MAPK
0.0107
uM
10694.149
 1.0162 1.0137 2.3563
Hs 578T
TNBC
Basal B
 FR180204
ERK1/2
MAPK
0.0533
uM
10694.149
 1.0423 1.0355 2.3563
Hs 578T
TNBC
Basal B
 FR180204
ERK1/2
MAPK
0.267
uM
10694.149
 0.9723 0.9763 2.3563
Hs 578T
TNBC
Basal B
 FR180204
ERK1/2
MAPK
1.33
uM
10694.149
 0.9823 0.9849 2.3563
Hs 578T
TNBC
Basal B
 FR180204
ERK1/2
MAPK
6.67
uM
10694.149
 0.9766 0.9800 2.3563
Hs 578T
TNBC
Basal B
 FR180204
ERK1/2
MAPK
33.3
uM
10694.149
 0.9468 0.9542 2.3563
LY2
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.0000853
uM
10816.149
 1.0371 1.1669 0.4545
LY2
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.000427
uM
10816.149
 1.3002 2.5638 0.4545
LY2
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.00213
uM
10816.149
 1.0755 1.3472 0.4545
LY2
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.0107
uM
10816.149
 1.0730 1.3352 0.4545
LY2
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.0533
uM
10816.149
 0.9629 0.8403 0.4545
LY2
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.267
uM
10816.149
 1.1468 1.7036 0.4545
LY2
HR+
Luminal
 FR180204
ERK1/2
MAPK
1.33
uM
10816.149
 1.1447 1.6926 0.4545
LY2
HR+
Luminal
 FR180204
ERK1/2
MAPK
6.67
uM
10816.149
 1.1761 1.8579 0.4545
LY2
HR+
Luminal
 FR180204
ERK1/2
MAPK
33.3
uM
10816.149
 1.1951 1.9605 0.4545
LY2
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.000256
uM
12319.166
 0.9630 0.9461 1.3789
LY2
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.00128
uM
12319.166
 0.7764 0.6646 1.3789
LY2
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.0064
uM
12319.166
 0.9263 0.8920 1.3789
LY2
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.032
uM
12319.166
 0.8068 0.7117 1.3789
LY2
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.16
uM
12319.166
 0.8436 0.7679 1.3789
LY2
HR+
Luminal
 FR180204
ERK1/2
MAPK
0.8
uM
12319.166
 0.8171 0.7274 1.3789
LY2
HR+
Luminal
 FR180204
ERK1/2
MAPK
4
uM
12319.166
 0.8648 0.8001 1.3789
LY2
HR+
Luminal
 FR180204
ERK1/2
MAPK
20
uM
12319.166
 0.8303 0.7477 1.3789
LY2
HR+
Luminal
 FR180204
ERK1/2
MAPK
100
uM
12319.166
 0.6475 0.4592 1.3789