Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 10031.002 | 0.9624 | 0.8851 | 0.6483 | |
| HCC1428 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 10031.002 | 0.9117 | 0.7341 | 0.6483 | |
| HCC1428 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 10031.002 | 0.8961 | 0.6886 | 0.6483 | |
| HCC1428 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 10031.002 | 0.8231 | 0.4812 | 0.6483 | |
| HCC1428 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 10031.002 | 0.8786 | 0.6382 | 0.6483 | |
| HCC1428 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 10031.002 | 0.8537 | 0.5669 | 0.6483 | |
| HCC1569 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9347.002 | 1.0095 | 1.0128 | 1.4904 | |
| HCC1569 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9347.002 | 1.0641 | 1.0852 | 1.4904 | |
| HCC1569 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9347.002 | 0.8731 | 0.8259 | 1.4904 | |
| HCC1569 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9347.002 | 0.8005 | 0.7226 | 1.4904 | |
| HCC1569 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 9347.002 | 0.5906 | 0.4047 | 1.4904 | |
| HCC1569 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 9347.002 | 0.6667 | 0.5237 | 1.4904 | |
| HCC1569 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 9347.002 | 0.6596 | 0.5128 | 1.4904 | |
| HCC1569 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 9347.002 | 0.7020 | 0.5774 | 1.4904 | |
| HCC1569 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 9347.002 | 0.6576 | 0.5098 | 1.4904 | |
| HCC1569 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 13038.002 | 1.0117 | 1.0194 | 1.2045 | |
| HCC1569 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 13038.002 | 1.0393 | 1.0651 | 1.2045 | |
| HCC1569 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 13038.002 | 0.9814 | 0.9691 | 1.2045 | |
| HCC1569 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 13038.002 | 0.8037 | 0.6681 | 1.2045 | |
| HCC1569 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 13038.002 | 0.5901 | 0.2907 | 1.2045 | |
| HCC1569 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 13038.002 | 0.5141 | 0.1511 | 1.2045 | |
| HCC1569 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 13038.002 | 0.5870 | 0.2852 | 1.2045 | |
| HCC1569 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 13038.002 | 0.5233 | 0.1682 | 1.2045 | |
| HCC1569 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 13038.002 | 0.4890 | 0.1042 | 1.2045 | |
| HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7829.002 | 1.0042 | 1.0044 | 1.8681 |