Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9278.002 | 0.7185 | -0.1782 | 0.3717 | |
| HCC1419 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9278.002 | 0.7017 | -0.2289 | 0.3717 | |
| HCC1419 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9278.002 | 0.7238 | -0.1617 | 0.3717 | |
| HCC1419 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9278.002 | 0.6998 | -0.2346 | 0.3717 | |
| HCC1419 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 10019.002 | 1.0516 | 1.2742 | 0.3915 | |
| HCC1419 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 10019.002 | 1.0808 | 1.4393 | 0.3915 | |
| HCC1419 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 10019.002 | 1.0018 | 1.0092 | 0.3915 | |
| HCC1419 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 10019.002 | 1.0643 | 1.3452 | 0.3915 | |
| HCC1419 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 10019.002 | 0.9807 | 0.9028 | 0.3915 | |
| HCC1419 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 10019.002 | 0.8572 | 0.3492 | 0.3915 | |
| HCC1419 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 10019.002 | 0.8558 | 0.3434 | 0.3915 | |
| HCC1419 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 10019.002 | 0.9058 | 0.5532 | 0.3915 | |
| HCC1419 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 10019.002 | 0.8663 | 0.3860 | 0.3915 | |
| HCC1428 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9294.002 | 1.0158 | 1.0424 | 0.7467 | |
| HCC1428 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9294.002 | 1.0199 | 1.0534 | 0.7467 | |
| HCC1428 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9294.002 | 0.9817 | 0.9512 | 0.7467 | |
| HCC1428 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9294.002 | 0.8885 | 0.7071 | 0.7467 | |
| HCC1428 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9294.002 | 0.8041 | 0.4936 | 0.7467 | |
| HCC1428 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9294.002 | 0.7540 | 0.3703 | 0.7467 | |
| HCC1428 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9294.002 | 0.7221 | 0.2931 | 0.7467 | |
| HCC1428 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9294.002 | 0.7296 | 0.3113 | 0.7467 | |
| HCC1428 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9294.002 | 0.7314 | 0.3155 | 0.7467 | |
| HCC1428 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 10031.002 | 1.0174 | 1.0540 | 0.6483 | |
| HCC1428 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 10031.002 | 1.0620 | 1.1945 | 0.6483 | |
| HCC1428 | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 10031.002 | 1.0207 | 1.0642 | 0.6483 |