Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
HCC1395	TNBC	Basal B	Docetaxel	TUBB	TUBB	2	uM	9254.002	0.5655	-0.5219	0.3983
HCC1395	TNBC	Basal B	Docetaxel	TUBB	TUBB	10	uM	9254.002	0.6454	-0.3338	0.3983
HCC1395	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.0000256	uM	9258.002	1.0203	1.0577	0.7065
HCC1395	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.000128	uM	9258.002	0.9970	0.9915	0.7065
HCC1395	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.00064	uM	9258.002	0.9713	0.9193	0.7065
HCC1395	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.0032	uM	9258.002	0.9103	0.7508	0.7065
HCC1395	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.016	uM	9258.002	0.4995	-0.2512	0.7065
HCC1395	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.08	uM	9258.002	0.2854	-0.6610	0.7065
HCC1395	TNBC	Basal B	Docetaxel	TUBB	TUBB	0.4	uM	9258.002	0.3063	-0.6253	0.7065
HCC1395	TNBC	Basal B	Docetaxel	TUBB	TUBB	2	uM	9258.002	0.2995	-0.6370	0.7065
HCC1395	TNBC	Basal B	Docetaxel	TUBB	TUBB	10	uM	9258.002	0.3405	-0.5647	0.7065
HCC1419	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.0000256	uM	7820.002	1.0092	1.0260	0.7084
HCC1419	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.000128	uM	7820.002	1.1148	1.3315	0.7084
HCC1419	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.00064	uM	7820.002	1.0179	1.0508	0.7084
HCC1419	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.0032	uM	7820.002	1.0619	1.1770	0.7084
HCC1419	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.016	uM	7820.002	0.9817	0.9485	0.7084
HCC1419	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.08	uM	7820.002	0.8966	0.7145	0.7084
HCC1419	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.4	uM	7820.002	0.8042	0.4703	0.7084
HCC1419	HER2amp	Luminal	Docetaxel	TUBB	TUBB	2	uM	7820.002	0.8692	0.6409	0.7084
HCC1419	HER2amp	Luminal	Docetaxel	TUBB	TUBB	10	uM	7820.002	0.8812	0.6729	0.7084
HCC1419	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.0000256	uM	9278.002	1.0175	1.0953	0.3717
HCC1419	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.000128	uM	9278.002	1.1170	1.6935	0.3717
HCC1419	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.00064	uM	9278.002	0.9406	0.6963	0.3717
HCC1419	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.0032	uM	9278.002	0.9787	0.8874	0.3717
HCC1419	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.016	uM	9278.002	0.8652	0.3547	0.3717

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)