Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
---|---|---|---|---|---|---|---|---|---|---|---|---|
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7829.002 | 1.0321 | 1.0341 | 1.8681 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7829.002 | 1.0180 | 1.0192 | 1.8681 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7829.002 | 0.3256 | 0.0970 | 1.8681 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 7829.002 | 0.1163 | -0.3678 | 1.8681 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 7829.002 | 0.0506 | -0.5952 | 1.8681 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 7829.002 | 0.0440 | -0.6241 | 1.8681 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 7829.002 | 0.0734 | -0.5058 | 1.8681 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 7829.002 | 0.1077 | -0.3932 | 1.8681 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9376.002 | 1.0915 | 1.1197 | 1.5057 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9376.002 | 1.1006 | 1.1315 | 1.5057 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9376.002 | 0.9716 | 0.9621 | 1.5057 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9376.002 | 0.5187 | 0.2933 | 1.5057 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 9376.002 | 0.2514 | -0.2005 | 1.5057 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 9376.002 | 0.1681 | -0.3882 | 1.5057 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 9376.002 | 0.1524 | -0.4267 | 1.5057 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 9376.002 | 0.2179 | -0.2730 | 1.5057 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 9376.002 | 0.1705 | -0.3824 | 1.5057 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 12702.002 | 0.9834 | 0.9822 | 1.8712 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 12702.002 | 1.0322 | 1.0342 | 1.8712 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 12702.002 | 0.8078 | 0.7844 | 1.8712 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 12702.002 | 0.2070 | -0.1381 | 1.8712 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 12702.002 | 0.0870 | -0.4576 | 1.8712 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 12702.002 | 0.0585 | -0.5613 | 1.8712 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 12702.002 | 0.0592 | -0.5586 | 1.8712 | |
HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 12702.002 | 0.0885 | -0.4526 | 1.8712 |