Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 7900.017 | 0.0619 | -0.9886 | 0.5383 | |
| MDA-MB-453 | TNBC | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7903.017 | 0.9854 | 0.9749 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7903.017 | 1.0003 | 1.0004 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 7903.017 | 0.9904 | 0.9834 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7903.017 | 0.9765 | 0.9594 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 7903.017 | 0.6887 | 0.4511 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 7903.017 | 0.0530 | -0.8403 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 7903.017 | 0.0200 | -0.9310 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 7903.017 | 0.0083 | -0.9675 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 7903.017 | 0.0003 | -0.9984 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 9708.017 | 1.0521 | 1.0949 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 9708.017 | 0.9772 | 0.9583 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 9708.017 | 1.0531 | 1.0968 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 9708.017 | 0.9329 | 0.8770 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 9708.017 | 0.6304 | 0.3122 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 9708.017 | 0.1438 | -0.6596 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 9708.017 | 0.0687 | -0.8267 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 9708.017 | 0.0338 | -0.9093 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 9708.017 | 0.0003 | -0.9990 | 1.0949 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7904.017 | 0.9621 | 0.9457 | 1.4023 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7904.017 | 0.8428 | 0.7704 | 1.4023 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.011 | uM | 7904.017 | 1.1970 | 1.2736 | 1.4023 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7904.017 | 0.7736 | 0.6654 | 1.4023 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.276 | uM | 7904.017 | 0.8718 | 0.8136 | 1.4023 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 1.38 | uM | 7904.017 | 0.4783 | 0.1820 | 1.4023 |