Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 6.9 | uM | 7904.017 | 0.1320 | -0.5280 | 1.4023 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 34.5 | uM | 7904.017 | 0.0209 | -0.8732 | 1.4023 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 172 | uM | 7904.017 | 0.4716 | 0.1701 | 1.4023 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7905.035 | 0.9794 | 0.9520 | 0.8588 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7905.035 | 0.7972 | 0.5359 | 0.8588 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.011 | uM | 7905.035 | 0.9490 | 0.8818 | 0.8588 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7905.035 | 0.8049 | 0.5534 | 0.8588 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.276 | uM | 7905.035 | 0.9138 | 0.8007 | 0.8588 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 1.38 | uM | 7905.035 | 0.3502 | -0.4106 | 0.8588 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 6.9 | uM | 7905.035 | 0.0488 | -0.9407 | 0.8588 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 34.5 | uM | 7905.035 | 0.0069 | -0.9939 | 0.8588 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 172 | uM | 7905.035 | 0.0003 | -0.9999 | 0.8588 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7906.017 | 1.1523 | 1.8984 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7906.017 | 0.7413 | -0.0863 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.011 | uM | 7906.017 | 1.2585 | 2.6505 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7906.017 | 0.9556 | 0.7758 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.276 | uM | 7906.017 | 1.1774 | 2.0663 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 1.38 | uM | 7906.017 | 0.6558 | -0.3369 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 6.9 | uM | 7906.017 | 0.2747 | -0.9320 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 34.5 | uM | 7906.017 | 0.0860 | -0.9968 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 172 | uM | 7906.017 | 0.0110 | -1.0000 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7907.017 | 1.1797 | 1.2477 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7907.017 | 0.6990 | 0.5530 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.011 | uM | 7907.017 | 1.1449 | 1.2006 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7907.017 | 0.8381 | 0.7654 | 1.4157 |