Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 7862.017 | 0.0002 | -0.9973 | 1.3198 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7863.017 | 0.9937 | 0.9936 | 1.9568 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7863.017 | 0.9644 | 0.9633 | 1.9568 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.011 | uM | 7863.017 | 1.0785 | 1.0787 | 1.9568 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7863.017 | 1.0128 | 1.0131 | 1.9568 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.276 | uM | 7863.017 | 0.6900 | 0.6545 | 1.9568 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 1.38 | uM | 7863.017 | 0.2588 | 0.0024 | 1.9568 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 6.9 | uM | 7863.017 | 0.0750 | -0.4675 | 1.9568 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 34.5 | uM | 7863.017 | 0.0638 | -0.5100 | 1.9568 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 7863.017 | 0.0002 | -0.9777 | 1.9568 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7864.017 | 0.9321 | 0.9168 | 1.6561 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7864.017 | 1.0412 | 1.0494 | 1.6561 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.011 | uM | 7864.017 | 0.9627 | 0.9546 | 1.6561 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7864.017 | 0.9947 | 0.9935 | 1.6561 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.276 | uM | 7864.017 | 0.6968 | 0.6080 | 1.6561 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 1.38 | uM | 7864.017 | 0.2510 | -0.1320 | 1.6561 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 6.9 | uM | 7864.017 | 0.0846 | -0.5499 | 1.6561 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 34.5 | uM | 7864.017 | 0.0606 | -0.6319 | 1.6561 | |
| Hs 578T | TNBC | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 7864.017 | 0.0002 | -0.9870 | 1.6561 | |
| LY2 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7865.017 | 0.7857 | 0.7632 | 1.9138 | |
| LY2 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7865.017 | 0.6826 | 0.6382 | 1.9138 | |
| LY2 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 7865.017 | 0.7087 | 0.6706 | 1.9138 | |
| LY2 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7865.017 | 0.7319 | 0.6991 | 1.9138 | |
| LY2 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 7865.017 | 0.6375 | 0.5807 | 1.9138 | |
| LY2 | HR+ | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 7865.017 | 0.5174 | 0.4174 | 1.9138 |