Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 600MPE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9118.002 | 0.7532 | 0.5012 | 0.9880 | |
| 600MPE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9118.002 | 0.6726 | 0.3388 | 0.9880 | |
| 600MPE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9118.002 | 0.7057 | 0.4055 | 0.9880 | |
| 600MPE | HR+ | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9118.002 | 0.8445 | 0.6855 | 0.9880 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7793.002 | 1.0110 | 1.0190 | 1.1545 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7793.002 | 1.0271 | 1.0469 | 1.1545 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7793.002 | 1.0237 | 1.0410 | 1.1545 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7793.002 | 0.8583 | 0.7522 | 1.1545 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 7793.002 | 0.1326 | -0.6525 | 1.1545 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 7793.002 | 0.0389 | -0.8798 | 1.1545 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 7793.002 | 0.0469 | -0.8587 | 1.1545 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 7793.002 | 0.0502 | -0.8502 | 1.1545 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 7793.002 | 0.0446 | -0.8647 | 1.1545 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 9146.002 | 1.0464 | 1.0732 | 1.2611 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 9146.002 | 1.0299 | 1.0473 | 1.2611 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 9146.002 | 1.0700 | 1.1102 | 1.2611 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0032 | uM | 9146.002 | 0.9121 | 0.8593 | 1.2611 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.016 | uM | 9146.002 | 0.1267 | -0.6113 | 1.2611 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.08 | uM | 9146.002 | 0.0955 | -0.6895 | 1.2611 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.4 | uM | 9146.002 | 0.0882 | -0.7085 | 1.2611 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 2 | uM | 9146.002 | 0.1018 | -0.6733 | 1.2611 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 10 | uM | 9146.002 | 0.1168 | -0.6357 | 1.2611 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 13030.002 | 1.0656 | 1.2344 | 0.5732 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.000128 | uM | 13030.002 | 0.9694 | 0.8944 | 0.5732 | |
| AU565 | HER2amp | Luminal | Docetaxel | TUBB | TUBB | 0.00064 | uM | 13030.002 | 0.9423 | 0.8029 | 0.5732 |