Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.0552 | uM | 9453.017 | 0.9583 | 0.9318 | 1.2279 | |
| HCC38 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 0.276 | uM | 9453.017 | 0.1798 | -0.5054 | 1.2279 | |
| HCC38 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 1.38 | uM | 9453.017 | 0.0689 | -0.7737 | 1.2279 | |
| HCC38 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 6.9 | uM | 9453.017 | 0.0523 | -0.8191 | 1.2279 | |
| HCC38 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 34.5 | uM | 9453.017 | 0.0409 | -0.8519 | 1.2279 | |
| HCC38 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 9453.017 | 0.0008 | -0.9939 | 1.2279 | |
| HCC70 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7857.017 | 0.9380 | 0.8947 | 1.1840 | |
| HCC70 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7857.017 | 0.9639 | 0.9389 | 1.1840 | |
| HCC70 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.011 | uM | 7857.017 | 1.0058 | 1.0097 | 1.1840 | |
| HCC70 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7857.017 | 0.9203 | 0.8644 | 1.1840 | |
| HCC70 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.276 | uM | 7857.017 | 0.8409 | 0.7277 | 1.1840 | |
| HCC70 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 1.38 | uM | 7857.017 | 0.1202 | -0.6658 | 1.1840 | |
| HCC70 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 6.9 | uM | 7857.017 | 0.0107 | -0.9567 | 1.1840 | |
| HCC70 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 34.5 | uM | 7857.017 | 0.0112 | -0.9551 | 1.1840 | |
| HCC70 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 172 | uM | 7857.017 | 0.0010 | -0.9940 | 1.1840 | |
| HCC70 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7860.017 | 1.0405 | 1.1325 | 0.6196 | |
| HCC70 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7860.017 | 0.9449 | 0.8250 | 0.6196 | |
| HCC70 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.011 | uM | 7860.017 | 1.0022 | 1.0072 | 0.6196 | |
| HCC70 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7860.017 | 0.9904 | 0.9692 | 0.6196 | |
| HCC70 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.276 | uM | 7860.017 | 0.9069 | 0.7083 | 0.6196 | |
| HCC70 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 1.38 | uM | 7860.017 | 0.4865 | -0.3749 | 0.6196 | |
| HCC70 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 6.9 | uM | 7860.017 | 0.0144 | -0.9979 | 0.6196 | |
| HCC70 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 34.5 | uM | 7860.017 | 0.0181 | -0.9969 | 0.6196 | |
| HCC70 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 172 | uM | 7860.017 | 0.0025 | -0.9999 | 0.6196 | |
| HMT-3522 S1 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7911.017 | 1.0763 | 1.0931 | 1.6151 |