Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

 Full screen view
Filter results: >>>>
Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
0.0273
uM
7904.077
 1.1302 1.1687 1.5112
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
0.136
uM
7904.077
 1.1320 1.1710 1.5112
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
0.682
uM
7904.077
 1.0442 1.0580 1.5112
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
3.41
uM
7904.077
 0.9085 0.8770 1.5112
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
17.1
uM
7904.077
 0.8420 0.7849 1.5112
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
85.2
uM
7904.077
 0.3665 0.0294 1.5112
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
0.000189
uM
7905.007
 0.9595 0.9049 0.8475
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
0.000945
uM
7905.007
 0.8503 0.6516 0.8475
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
0.00472
uM
7905.007
 0.8403 0.6287 0.8475
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
0.0236
uM
7905.007
 1.0401 1.0950 0.8475
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
0.118
uM
7905.007
 1.0767 1.1822 0.8475
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
0.59
uM
7905.007
 0.8834 0.7278 0.8475
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
2.95
uM
7905.007
 0.9319 0.8403 0.8475
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
14.8
uM
7905.007
 0.4589 -0.2024 0.8475
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
73.8
uM
7905.007
 0.0884 -0.8858 0.8475
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
0.000189
uM
7906.007
 0.9356 0.7963 0.6194
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
0.000945
uM
7906.007
 1.6045 3.2913 0.6194
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
0.00472
uM
7906.007
 0.8538 0.5495 0.6194
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
0.0236
uM
7906.007
 0.9817 0.9412 0.6194
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
0.118
uM
7906.007
 1.2049 1.7023 0.6194
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
0.59
uM
7906.007
 0.8676 0.5901 0.6194
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
2.95
uM
7906.007
 0.8607 0.5699 0.6194
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
14.8
uM
7906.007
 0.9845 0.9501 0.6194
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
73.8
uM
7906.007
 0.1001 -0.9513 0.6194
MDA-MB-468
TNBC
Basal A
 CPT-11
TOP1
TOP
0.000189
uM
7907.043
 0.9946 0.9934 1.6330