Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.682 | uM | 9708.121 | 0.9921 | 0.9861 | 1.1394 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 3.41 | uM | 9708.121 | 0.8950 | 0.8144 | 1.1394 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 17.1 | uM | 9708.121 | 0.3604 | -0.1833 | 1.1394 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 85.2 | uM | 9708.121 | 0.2094 | -0.4928 | 1.1394 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.000218 | uM | 9723.121 | 1.0587 | 1.1245 | 0.9445 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.00109 | uM | 9723.121 | 1.1456 | 1.3095 | 0.9445 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.00546 | uM | 9723.121 | 1.0519 | 1.1101 | 0.9445 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.0273 | uM | 9723.121 | 1.0363 | 1.0770 | 0.9445 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.136 | uM | 9723.121 | 1.0620 | 1.1314 | 0.9445 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.682 | uM | 9723.121 | 0.9938 | 0.9869 | 0.9445 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 3.41 | uM | 9723.121 | 0.8363 | 0.6551 | 0.9445 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 17.1 | uM | 9723.121 | 0.5829 | 0.1294 | 0.9445 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 85.2 | uM | 9723.121 | 0.2534 | -0.5324 | 0.9445 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.000218 | uM | 10270.121 | 1.1252 | 1.3081 | 0.8235 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.00109 | uM | 10270.121 | 1.0614 | 1.1501 | 0.8235 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.00546 | uM | 10270.121 | 1.0027 | 1.0067 | 0.8235 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.0273 | uM | 10270.121 | 1.0050 | 1.0121 | 0.8235 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.136 | uM | 10270.121 | 0.9599 | 0.9029 | 0.8235 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 0.682 | uM | 10270.121 | 0.8834 | 0.7204 | 0.8235 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 3.41 | uM | 10270.121 | 0.8106 | 0.5499 | 0.8235 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 17.1 | uM | 10270.121 | 0.4828 | -0.1739 | 0.8235 | |
| MDA-MB-453 | TNBC | Luminal | CPT-11 | TOP1 | TOP | 85.2 | uM | 10270.121 | 0.2090 | -0.7011 | 0.8235 | |
| MDA-MB-468 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.000218 | uM | 7904.077 | 0.9076 | 0.8757 | 1.5112 | |
| MDA-MB-468 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.00109 | uM | 7904.077 | 1.1594 | 1.2057 | 1.5112 | |
| MDA-MB-468 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.00546 | uM | 7904.077 | 0.9047 | 0.8717 | 1.5112 |