Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HBL-100 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 0.000945 | uM | 9226.034 | 0.9966 | 0.9974 | 2.6175 | |
| HBL-100 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 0.00472 | uM | 9226.034 | 1.0415 | 1.0313 | 2.6175 | |
| HBL-100 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 0.0236 | uM | 9226.034 | 0.9958 | 0.9968 | 2.6175 | |
| HBL-100 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 0.118 | uM | 9226.034 | 0.9814 | 0.9857 | 2.6175 | |
| HBL-100 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 0.59 | uM | 9226.034 | 0.9011 | 0.9220 | 2.6175 | |
| HBL-100 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 2.95 | uM | 9226.034 | 0.4484 | 0.4721 | 2.6175 | |
| HBL-100 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 14.8 | uM | 9226.034 | 0.0273 | -0.4947 | 2.6175 | |
| HBL-100 | Unknown | Unknown | CPT-11 | TOP1 | TOP | 73.8 | uM | 9226.034 | 0.0100 | -0.6561 | 2.6175 | |
| HCC1143 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.000189 | uM | 7810.007 | 0.9498 | 0.8958 | 0.9616 | |
| HCC1143 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.000945 | uM | 7810.007 | 1.0520 | 1.1082 | 0.9616 | |
| HCC1143 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.00472 | uM | 7810.007 | 1.0006 | 1.0013 | 0.9616 | |
| HCC1143 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.0236 | uM | 7810.007 | 1.0527 | 1.1097 | 0.9616 | |
| HCC1143 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.118 | uM | 7810.007 | 1.0703 | 1.1464 | 0.9616 | |
| HCC1143 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.59 | uM | 7810.007 | 1.0690 | 1.1437 | 0.9616 | |
| HCC1143 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 2.95 | uM | 7810.007 | 1.0082 | 1.0170 | 0.9616 | |
| HCC1143 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 14.8 | uM | 7810.007 | 0.7024 | 0.3852 | 0.9616 | |
| HCC1143 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 73.8 | uM | 7810.007 | 0.3521 | -0.3245 | 0.9616 | |
| HCC1143 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.000218 | uM | 9233.121 | 1.0645 | 1.1364 | 0.9468 | |
| HCC1143 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.00109 | uM | 9233.121 | 1.1097 | 1.2325 | 0.9468 | |
| HCC1143 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.00546 | uM | 9233.121 | 1.0212 | 1.0447 | 0.9468 | |
| HCC1143 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.0273 | uM | 9233.121 | 1.0195 | 1.0412 | 0.9468 | |
| HCC1143 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.136 | uM | 9233.121 | 1.0515 | 1.1090 | 0.9468 | |
| HCC1143 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 0.682 | uM | 9233.121 | 1.0104 | 1.0219 | 0.9468 | |
| HCC1143 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 3.41 | uM | 9233.121 | 0.8512 | 0.6870 | 0.9468 | |
| HCC1143 | TNBC | Basal A | CPT-11 | TOP1 | TOP | 17.1 | uM | 9233.121 | 0.7948 | 0.5691 | 0.9468 |