Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 10266.131 | 0.8082 | 0.5591 | 0.8552 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 10266.131 | 0.7317 | 0.3880 | 0.8552 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 10266.131 | 0.3071 | -0.4971 | 0.8552 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 10266.131 | 0.1063 | -0.8545 | 0.8552 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7903.017 | 1.0382 | 1.0655 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7903.017 | 1.0160 | 1.0276 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7903.017 | 1.0284 | 1.0488 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7903.017 | 0.9935 | 0.9889 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7903.017 | 1.0098 | 1.0169 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7903.017 | 0.9162 | 0.8550 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7903.017 | 0.6261 | 0.3370 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7903.017 | 0.1119 | -0.6960 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7903.017 | 0.0152 | -0.9454 | 1.1625 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9708.017 | 1.0086 | 1.0157 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9708.017 | 0.9911 | 0.9837 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9708.017 | 1.0610 | 1.1111 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9708.017 | 0.9951 | 0.9910 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9708.017 | 1.0353 | 1.0644 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9708.017 | 0.9218 | 0.8567 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9708.017 | 0.6114 | 0.2761 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9708.017 | 0.1281 | -0.6938 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9708.017 | 0.0747 | -0.8130 | 1.0949 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00128 | uM | 9723.049 | 1.1570 | 1.3310 | 0.9525 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0064 | uM | 9723.049 | 0.9639 | 0.9243 | 0.9525 | |
| MDA-MB-453 | TNBC | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.032 | uM | 9723.049 | 1.1329 | 1.2800 | 0.9525 |