Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7899.017 | 0.3721 | 0.2318 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7899.017 | 0.3418 | 0.1815 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7900.017 | 1.4715 | 3.0989 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7900.017 | 1.0487 | 1.1848 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7900.017 | 1.1646 | 1.6541 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7900.017 | 1.0496 | 1.1882 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7900.017 | 1.3311 | 2.4020 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7900.017 | 0.8612 | 0.5151 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7900.017 | 1.1585 | 1.6285 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7900.017 | 0.4919 | -0.4646 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7900.017 | 0.1849 | -0.9130 | 0.5383 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7902.13 | 1.2664 | 1.2862 | 1.7664 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7902.13 | 0.8773 | 0.8572 | 1.7664 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7902.13 | 1.3393 | 1.3597 | 1.7664 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7902.13 | 0.9717 | 0.9678 | 1.7664 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7902.13 | 1.1510 | 1.1657 | 1.7664 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7902.13 | 0.8161 | 0.7827 | 1.7664 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7902.13 | 0.6884 | 0.6190 | 1.7664 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7902.13 | 0.3452 | 0.0952 | 1.7664 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7902.13 | 0.1214 | -0.3940 | 1.7664 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 10266.131 | 1.1417 | 1.3352 | 0.8552 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 10266.131 | 0.7982 | 0.5366 | 0.8552 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 10266.131 | 1.1396 | 1.3302 | 0.8552 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 10266.131 | 0.9667 | 0.9224 | 0.8552 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 10266.131 | 0.9174 | 0.8081 | 0.8552 |