Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00128 | uM | 9664.049 | 1.0325 | 1.0910 | 0.7193 | |
| MDA-MB-415 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0064 | uM | 9664.049 | 1.0726 | 1.2048 | 0.7193 | |
| MDA-MB-415 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.032 | uM | 9664.049 | 1.0549 | 1.1543 | 0.7193 | |
| MDA-MB-415 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.16 | uM | 9664.049 | 1.0427 | 1.1198 | 0.7193 | |
| MDA-MB-415 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.8 | uM | 9664.049 | 1.1029 | 1.2917 | 0.7193 | |
| MDA-MB-415 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 4 | uM | 9664.049 | 1.0360 | 1.1008 | 0.7193 | |
| MDA-MB-415 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 20 | uM | 9664.049 | 1.0232 | 1.0647 | 0.7193 | |
| MDA-MB-415 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 100 | uM | 9664.049 | 1.1349 | 1.3848 | 0.7193 | |
| MDA-MB-415 | HR+ | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 500 | uM | 9664.049 | 1.1469 | 1.4199 | 0.7193 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7898.017 | 1.0809 | 1.1393 | 1.1556 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7898.017 | 0.8985 | 0.8231 | 1.1556 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7898.017 | 1.0652 | 1.1124 | 1.1556 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7898.017 | 0.9244 | 0.8684 | 1.1556 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7898.017 | 1.0585 | 1.1008 | 1.1556 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7898.017 | 0.8615 | 0.7579 | 1.1556 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7898.017 | 0.7376 | 0.5370 | 1.1556 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7898.017 | 0.3267 | -0.2405 | 1.1556 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7898.017 | 0.1398 | -0.6357 | 1.1556 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7899.017 | 1.1732 | 1.1629 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7899.017 | 0.8588 | 0.8562 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7899.017 | 1.1568 | 1.1481 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7899.017 | 0.9828 | 0.9831 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7899.017 | 1.0886 | 1.0850 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7899.017 | 0.7656 | 0.7545 | 2.0395 | |
| MDA-MB-436 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7899.017 | 0.6703 | 0.6438 | 2.0395 |