Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7870.017 | 0.0373 | -0.5994 | 2.0447 | |
| MCF 10A | NM | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7870.017 | 0.0030 | -0.8833 | 2.0447 | |
| MCF 10A | NM | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9551.017 | 1.0850 | 1.0640 | 2.5886 | |
| MCF 10A | NM | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9551.017 | 1.0447 | 1.0341 | 2.5886 | |
| MCF 10A | NM | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9551.017 | 1.0829 | 1.0625 | 2.5886 | |
| MCF 10A | NM | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9551.017 | 1.0512 | 1.0389 | 2.5886 | |
| MCF 10A | NM | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9551.017 | 0.9651 | 0.9727 | 2.5886 | |
| MCF 10A | NM | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9551.017 | 0.8487 | 0.8772 | 2.5886 | |
| MCF 10A | NM | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9551.017 | 0.5544 | 0.5924 | 2.5886 | |
| MCF 10A | NM | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9551.017 | 0.2020 | 0.0782 | 2.5886 | |
| MCF 10A | NM | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9551.017 | 0.0060 | -0.7233 | 2.5886 | |
| MCF 10F | NM | - | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7872.017 | 1.0860 | 1.1119 | 1.5155 | |
| MCF 10F | NM | - | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7872.017 | 0.9688 | 0.9586 | 1.5155 | |
| MCF 10F | NM | - | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7872.017 | 0.9891 | 0.9856 | 1.5155 | |
| MCF 10F | NM | - | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7872.017 | 1.0296 | 1.0389 | 1.5155 | |
| MCF 10F | NM | - | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7872.017 | 0.9838 | 0.9786 | 1.5155 | |
| MCF 10F | NM | - | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7872.017 | 0.9400 | 0.9200 | 1.5155 | |
| MCF 10F | NM | - | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7872.017 | 0.7105 | 0.5962 | 1.5155 | |
| MCF 10F | NM | - | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7872.017 | 1.0222 | 1.0291 | 1.5155 | |
| MCF 10F | NM | - | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7872.017 | 1.0112 | 1.0147 | 1.5155 | |
| MCF 10F | NM | - | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9566.017 | 1.1765 | 1.1553 | 2.1734 | |
| MCF 10F | NM | - | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9566.017 | 0.9725 | 0.9745 | 2.1734 | |
| MCF 10F | NM | - | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9566.017 | 1.0403 | 1.0367 | 2.1734 | |
| MCF 10F | NM | - | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9566.017 | 0.8242 | 0.8298 | 2.1734 | |
| MCF 10F | NM | - | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9566.017 | 0.9981 | 0.9982 | 2.1734 |