Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7848.037 | 0.8495 | 0.4353 | 0.4916 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7848.037 | 0.4988 | -0.5142 | 0.4916 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7848.037 | 0.3671 | -0.7396 | 0.4916 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7848.037 | 0.3099 | -0.8155 | 0.4916 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7848.037 | 0.3161 | -0.8080 | 0.4916 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7848.05 | 1.0174 | 1.0799 | 0.4413 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7848.05 | 0.9980 | 0.9908 | 0.4413 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7848.05 | 1.0305 | 1.1408 | 0.4413 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7848.05 | 1.0460 | 1.2146 | 0.4413 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7848.05 | 0.7777 | 0.1314 | 0.4413 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7848.05 | 0.4755 | -0.6290 | 0.4413 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7848.05 | 0.3758 | -0.7824 | 0.4413 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7848.05 | 0.3241 | -0.8444 | 0.4413 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7848.05 | 0.1967 | -0.9498 | 0.4413 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7849.04 | 1.0112 | 1.0412 | 0.5448 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7849.04 | 0.9768 | 0.9158 | 0.5448 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7849.04 | 1.0530 | 1.1987 | 0.5448 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7849.04 | 1.0225 | 1.0834 | 0.5448 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7849.04 | 0.8037 | 0.3390 | 0.5448 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7849.04 | 0.2834 | -0.8024 | 0.5448 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7849.04 | 0.3308 | -0.7376 | 0.5448 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7849.04 | 0.2473 | -0.8461 | 0.5448 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7849.04 | 0.2184 | -0.8775 | 0.5448 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9420.037 | 0.9522 | 0.7619 | 0.3864 | |
| HCC2185 | TNBC | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9420.037 | 1.0418 | 1.2234 | 0.3864 |