Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 7813.037 | 0.6146 | 0.0102 | 0.7127 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 7813.037 | 0.5880 | -0.0506 | 0.7127 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 7813.037 | 0.3533 | -0.5356 | 0.7127 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7814.04 | 0.9876 | 0.9716 | 0.8711 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7814.04 | 0.9595 | 0.9072 | 0.8711 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7814.04 | 1.0138 | 1.0318 | 0.8711 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7814.04 | 0.8985 | 0.7688 | 0.8711 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7814.04 | 0.6553 | 0.2311 | 0.8711 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7814.04 | 0.4986 | -0.1004 | 0.8711 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 7814.04 | 0.4332 | -0.2345 | 0.8711 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 7814.04 | 0.3748 | -0.3517 | 0.8711 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 7814.04 | 0.1961 | -0.6919 | 0.8711 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7816.05 | 1.0307 | 1.0601 | 1.0200 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7816.05 | 1.0721 | 1.1413 | 1.0200 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7816.05 | 1.0360 | 1.0706 | 1.0200 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7816.05 | 1.0603 | 1.1183 | 1.0200 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7816.05 | 0.7336 | 0.4761 | 1.0200 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7816.05 | 0.5174 | 0.0483 | 1.0200 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 7816.05 | 0.4917 | -0.0029 | 1.0200 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 7816.05 | 0.3875 | -0.2105 | 1.0200 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 7816.05 | 0.4651 | -0.0558 | 1.0200 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9254.037 | 1.1564 | 1.3804 | 0.8345 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9254.037 | 1.1845 | 1.4499 | 0.8345 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9254.037 | 1.2266 | 1.5546 | 0.8345 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9254.037 | 0.8495 | 0.6448 | 0.8345 |