Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 100 | uM | 9233.037 | 0.1050 | -0.6831 | 1.2235 | |
| HCC1187 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7811.04 | 0.9746 | 0.8728 | 0.3921 | |
| HCC1187 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7811.04 | 0.7905 | 0.0982 | 0.3921 | |
| HCC1187 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7811.04 | 1.0260 | 1.1352 | 0.3921 | |
| HCC1187 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7811.04 | 0.9508 | 0.7584 | 0.3921 | |
| HCC1187 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7811.04 | 0.9767 | 0.8832 | 0.3921 | |
| HCC1187 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7811.04 | 0.9553 | 0.7799 | 0.3921 | |
| HCC1187 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 4 | uM | 7811.04 | 0.3201 | -0.8906 | 0.3921 | |
| HCC1187 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 20 | uM | 7811.04 | 0.3630 | -0.8491 | 0.3921 | |
| HCC1187 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 100 | uM | 7811.04 | 0.0158 | -1.0000 | 0.3921 | |
| HCC1187 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7812.04 | 1.0078 | 1.0148 | 1.0573 | |
| HCC1187 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7812.04 | 0.9135 | 0.8360 | 1.0573 | |
| HCC1187 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7812.04 | 1.0522 | 1.0986 | 1.0573 | |
| HCC1187 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7812.04 | 0.9314 | 0.8700 | 1.0573 | |
| HCC1187 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7812.04 | 0.9886 | 0.9784 | 1.0573 | |
| HCC1187 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7812.04 | 0.9921 | 0.9851 | 1.0573 | |
| HCC1187 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 4 | uM | 7812.04 | 0.7761 | 0.5737 | 1.0573 | |
| HCC1187 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 20 | uM | 7812.04 | 0.4225 | -0.1146 | 1.0573 | |
| HCC1187 | TNBC | Basal A | 17-AAG | HSP90 | HSP90 | 100 | uM | 7812.04 | 0.3542 | -0.2506 | 1.0573 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7813.037 | 1.2134 | 1.6235 | 0.7127 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7813.037 | 1.2429 | 1.7135 | 0.7127 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7813.037 | 1.2281 | 1.6684 | 0.7127 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7813.037 | 1.0901 | 1.2573 | 0.7127 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7813.037 | 0.9978 | 0.9938 | 0.7127 | |
| HCC1395 | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7813.037 | 0.8368 | 0.5577 | 0.7127 |