Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 10264.131 | 0.2827 | -0.1608 | 1.4548 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 10264.131 | 0.1376 | -0.4884 | 1.4548 | |
| LY2 | HR+ | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 10264.131 | 0.1240 | -0.5236 | 1.4548 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7867.017 | 0.9769 | 0.9816 | 2.5255 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7867.017 | 0.9352 | 0.9477 | 2.5255 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7867.017 | 0.7836 | 0.8159 | 2.5255 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7867.017 | 0.6780 | 0.7148 | 2.5255 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7867.017 | 0.4361 | 0.4399 | 2.5255 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7867.017 | 0.2120 | 0.0821 | 2.5255 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7867.017 | 0.0108 | -0.6674 | 2.5255 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7867.017 | 0.0066 | -0.7268 | 2.5255 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7867.017 | 0.0054 | -0.7470 | 2.5255 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7870.017 | 1.0560 | 1.0540 | 2.0447 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7870.017 | 1.0117 | 1.0114 | 2.0447 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7870.017 | 0.8795 | 0.8783 | 2.0447 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7870.017 | 0.8489 | 0.8460 | 2.0447 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7870.017 | 0.5069 | 0.4345 | 2.0447 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7870.017 | 0.2518 | 0.0188 | 2.0447 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7870.017 | 0.0164 | -0.7319 | 2.0447 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7870.017 | 0.0064 | -0.8306 | 2.0447 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7870.017 | 0.0057 | -0.8406 | 2.0447 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 9551.017 | 0.4127 | 0.4208 | 2.5886 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 9551.017 | 0.5727 | 0.6126 | 2.5886 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 9551.017 | 0.3623 | 0.3511 | 2.5886 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 9551.017 | 0.3496 | 0.3327 | 2.5886 |