Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 9551.017 | 0.3593 | 0.3467 | 2.5886 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 9551.017 | 0.1954 | 0.0644 | 2.5886 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 9551.017 | 0.0240 | -0.5266 | 2.5886 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 9551.017 | 0.0285 | -0.4939 | 2.5886 | |
| MCF 10A | NM | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 9551.017 | 0.0055 | -0.7313 | 2.5886 | |
| MCF 10F | NM | - | 5-FU | TYMS | TYMS | 0.0492 | uM | 7872.017 | 1.0455 | 1.0596 | 1.5155 | |
| MCF 10F | NM | - | 5-FU | TYMS | TYMS | 0.246 | uM | 7872.017 | 0.9949 | 0.9933 | 1.5155 | |
| MCF 10F | NM | - | 5-FU | TYMS | TYMS | 1.23 | uM | 7872.017 | 0.8707 | 0.8254 | 1.5155 | |
| MCF 10F | NM | - | 5-FU | TYMS | TYMS | 6.15 | uM | 7872.017 | 0.7697 | 0.6828 | 1.5155 | |
| MCF 10F | NM | - | 5-FU | TYMS | TYMS | 30.7 | uM | 7872.017 | 0.7547 | 0.6610 | 1.5155 | |
| MCF 10F | NM | - | 5-FU | TYMS | TYMS | 154 | uM | 7872.017 | 0.5975 | 0.4238 | 1.5155 | |
| MCF 10F | NM | - | 5-FU | TYMS | TYMS | 769 | uM | 7872.017 | 1.0064 | 1.0085 | 1.5155 | |
| MCF 10F | NM | - | 5-FU | TYMS | TYMS | 3840 | uM | 7872.017 | 1.0580 | 1.0758 | 1.5155 | |
| MCF 10F | NM | - | 5-FU | TYMS | TYMS | 19200 | uM | 7872.017 | 1.0095 | 1.0126 | 1.5155 | |
| MCF 10F | NM | - | 5-FU | TYMS | TYMS | 0.0492 | uM | 9566.017 | 0.5153 | 0.4742 | 2.1734 | |
| MCF 10F | NM | - | 5-FU | TYMS | TYMS | 0.246 | uM | 9566.017 | 0.4881 | 0.4378 | 2.1734 | |
| MCF 10F | NM | - | 5-FU | TYMS | TYMS | 1.23 | uM | 9566.017 | 0.3609 | 0.2514 | 2.1734 | |
| MCF 10F | NM | - | 5-FU | TYMS | TYMS | 6.15 | uM | 9566.017 | 0.3630 | 0.2546 | 2.1734 | |
| MCF 10F | NM | - | 5-FU | TYMS | TYMS | 30.7 | uM | 9566.017 | 0.3418 | 0.2204 | 2.1734 | |
| MCF 10F | NM | - | 5-FU | TYMS | TYMS | 154 | uM | 9566.017 | 0.1683 | -0.1190 | 2.1734 | |
| MCF 10F | NM | - | 5-FU | TYMS | TYMS | 769 | uM | 9566.017 | 0.0578 | -0.4611 | 2.1734 | |
| MCF 10F | NM | - | 5-FU | TYMS | TYMS | 3840 | uM | 9566.017 | 0.0444 | -0.5228 | 2.1734 | |
| MCF 10F | NM | - | 5-FU | TYMS | TYMS | 19200 | uM | 9566.017 | 0.3910 | 0.2984 | 2.1734 | |
| MCF12A | NM | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7873.017 | 1.0204 | 1.0183 | 2.2073 | |
| MCF12A | NM | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7873.017 | 1.0748 | 1.0664 | 2.2073 |