Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF12A | NM | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7873.017 | 0.9683 | 0.9710 | 2.2073 | |
| MCF12A | NM | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7873.017 | 0.6436 | 0.6381 | 2.2073 | |
| MCF12A | NM | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7873.017 | 0.5010 | 0.4624 | 2.2073 | |
| MCF12A | NM | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7873.017 | 0.2226 | 0.0126 | 2.2073 | |
| MCF12A | NM | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7873.017 | 0.0078 | -0.7776 | 2.2073 | |
| MCF12A | NM | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7873.017 | 0.0078 | -0.7776 | 2.2073 | |
| MCF12A | NM | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7873.017 | 0.0059 | -0.8046 | 2.2073 | |
| MCF7 | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 7875.017 | 1.1222 | 1.1484 | 1.6110 | |
| MCF7 | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 7875.017 | 1.0124 | 1.0154 | 1.6110 | |
| MCF7 | HR+ | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 7875.017 | 0.9506 | 0.9381 | 1.6110 | |
| MCF7 | HR+ | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 7875.017 | 0.7975 | 0.7379 | 1.6110 | |
| MCF7 | HR+ | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 7875.017 | 0.6313 | 0.5032 | 1.6110 | |
| MCF7 | HR+ | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 7875.017 | 0.5650 | 0.4031 | 1.6110 | |
| MCF7 | HR+ | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 7875.017 | 0.2969 | -0.0588 | 1.6110 | |
| MCF7 | HR+ | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 7875.017 | 0.1309 | -0.4340 | 1.6110 | |
| MCF7 | HR+ | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 7875.017 | 0.1168 | -0.4727 | 1.6110 | |
| MCF7 | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 9583.017 | 1.0625 | 1.1195 | 1.0456 | |
| MCF7 | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 9583.017 | 1.0481 | 1.0919 | 1.0456 | |
| MCF7 | HR+ | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 9583.017 | 0.9242 | 0.8547 | 1.0456 | |
| MCF7 | HR+ | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 9583.017 | 0.8471 | 0.7064 | 1.0456 | |
| MCF7 | HR+ | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 9583.017 | 0.7512 | 0.5213 | 1.0456 | |
| MCF7 | HR+ | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 9583.017 | 0.7228 | 0.4662 | 1.0456 | |
| MCF7 | HR+ | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 9583.017 | 0.4290 | -0.1098 | 1.0456 | |
| MCF7 | HR+ | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 9583.017 | 0.3001 | -0.3675 | 1.0456 | |
| MCF7 | HR+ | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 9583.017 | 0.2405 | -0.4881 | 1.0456 |