Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 7876.017 | 1.2931 | 1.9343 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 7876.017 | 0.9624 | 0.8888 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 7876.017 | 0.8228 | 0.4953 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 7876.017 | 0.9112 | 0.7411 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 7876.017 | 0.9058 | 0.7257 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 7876.017 | 0.5925 | -0.0836 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 7876.017 | 0.6533 | 0.0601 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 7876.017 | 0.4579 | -0.3760 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 7876.017 | 0.2719 | -0.7133 | 0.6706 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 7877.017 | 1.0201 | 1.0582 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 7877.017 | 1.0357 | 1.1033 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 7877.017 | 1.0405 | 1.1175 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 7877.017 | 1.0144 | 1.0415 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 7877.017 | 0.9937 | 0.9820 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 7877.017 | 0.9734 | 0.9238 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 7877.017 | 0.8040 | 0.4617 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 7877.017 | 0.7795 | 0.3978 | 0.6955 | |
| MDA-MB-134-VI | HR+ | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 7877.017 | 0.6415 | 0.0563 | 0.6955 | |
| MDA-MB-157 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7879.017 | 1.0255 | 1.0286 | 1.7754 | |
| MDA-MB-157 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7879.017 | 1.0407 | 1.0455 | 1.7754 | |
| MDA-MB-157 | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7879.017 | 1.0195 | 1.0219 | 1.7754 | |
| MDA-MB-157 | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7879.017 | 1.0314 | 1.0351 | 1.7754 | |
| MDA-MB-157 | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7879.017 | 0.9314 | 0.9216 | 1.7754 | |
| MDA-MB-157 | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7879.017 | 0.8259 | 0.7958 | 1.7754 | |
| MDA-MB-157 | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7879.017 | 0.6395 | 0.5548 | 1.7754 |