Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 7837.017 | 0.8961 | 0.8518 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 7837.017 | 0.8726 | 0.8176 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 7837.017 | 0.5849 | 0.3729 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 7837.017 | 0.3526 | -0.0375 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 7837.017 | 0.2422 | -0.2604 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 7837.017 | 0.1550 | -0.4591 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 7837.017 | 0.1129 | -0.5669 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 9386.017 | 0.9528 | 0.9304 | 1.3666 | |
| HCC1954 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 9386.017 | 1.0107 | 1.0156 | 1.3666 | |
| HCC1954 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 9386.017 | 0.8493 | 0.7747 | 1.3666 | |
| HCC1954 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 9386.017 | 0.7643 | 0.6429 | 1.3666 | |
| HCC1954 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 9386.017 | 0.5933 | 0.3650 | 1.3666 | |
| HCC1954 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 9386.017 | 0.4332 | 0.0845 | 1.3666 | |
| HCC1954 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 9386.017 | 0.2398 | -0.2966 | 1.3666 | |
| HCC1954 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 9386.017 | 0.1707 | -0.4515 | 1.3666 | |
| HCC1954 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 9386.017 | 0.1104 | -0.6011 | 1.3666 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 7846.017 | 1.0277 | 1.1674 | 0.3403 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 7846.017 | 1.0424 | 1.2594 | 0.3403 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 7846.017 | 1.0340 | 1.2062 | 0.3403 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 7846.017 | 1.0840 | 1.5352 | 0.3403 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 7846.017 | 1.0465 | 1.2856 | 0.3403 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 7846.017 | 0.9910 | 0.9477 | 0.3403 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 7846.017 | 0.8020 | 0.0458 | 0.3403 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 7846.017 | 0.6412 | -0.4583 | 0.3403 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 7846.017 | 0.4673 | -0.7862 | 0.3403 |