Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 7832.017 | 0.8234 | 0.7301 | 1.3404 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 7832.017 | 0.6954 | 0.5252 | 1.3404 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 7832.017 | 0.5178 | 0.2240 | 1.3404 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 7832.017 | 0.3710 | -0.0456 | 1.3404 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 7832.017 | 0.2398 | -0.3109 | 1.3404 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 7833.017 | 1.0165 | 1.0254 | 1.2975 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 7833.017 | 1.0011 | 1.0017 | 1.2975 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 7833.017 | 1.0053 | 1.0081 | 1.2975 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 7833.017 | 0.9802 | 0.9694 | 1.2975 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 7833.017 | 0.8985 | 0.8417 | 1.2975 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 7833.017 | 0.8287 | 0.7303 | 1.2975 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 7833.017 | 0.7415 | 0.5883 | 1.2975 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 7833.017 | 0.7158 | 0.5456 | 1.2975 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 7833.017 | 0.7635 | 0.6245 | 1.2975 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 7834.13 | 0.9724 | 0.9716 | 1.9535 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 7834.13 | 0.9937 | 0.9935 | 1.9535 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 7834.13 | 0.9897 | 0.9894 | 1.9535 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 7834.13 | 0.9271 | 0.9240 | 1.9535 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 7834.13 | 0.8426 | 0.8321 | 1.9535 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 7834.13 | 0.6683 | 0.6271 | 1.9535 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 7834.13 | 0.5183 | 0.4287 | 1.9535 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 7834.13 | 0.3814 | 0.2211 | 1.9535 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 7834.13 | 0.2873 | 0.0562 | 1.9535 | |
| HCC1954 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 7837.017 | 0.9437 | 0.9203 | 1.4255 | |
| HCC1954 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 7837.017 | 1.0421 | 1.0587 | 1.4255 |