Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 9347.017 | 0.4056 | 0.1477 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 9347.017 | 0.2690 | -0.1086 | 1.6249 | |
| HCC1569 | HER2amp | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 9347.017 | 0.1501 | -0.3774 | 1.6249 | |
| HCC1806 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 7829.017 | 1.0047 | 1.0048 | 1.9566 | |
| HCC1806 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 7829.017 | 0.9465 | 0.9446 | 1.9566 | |
| HCC1806 | TNBC | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 7829.017 | 0.8443 | 0.8343 | 1.9566 | |
| HCC1806 | TNBC | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 7829.017 | 0.7129 | 0.6824 | 1.9566 | |
| HCC1806 | TNBC | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 7829.017 | 0.5822 | 0.5169 | 1.9566 | |
| HCC1806 | TNBC | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 7829.017 | 0.3547 | 0.1775 | 1.9566 | |
| HCC1806 | TNBC | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 7829.017 | 0.2219 | -0.0734 | 1.9566 | |
| HCC1806 | TNBC | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 7829.017 | 0.1244 | -0.3108 | 1.9566 | |
| HCC1806 | TNBC | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 7829.017 | 0.0488 | -0.5726 | 1.9566 | |
| HCC1806 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 7830.017 | 1.0457 | 1.0526 | 1.7247 | |
| HCC1806 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 7830.017 | 0.8724 | 0.8478 | 1.7247 | |
| HCC1806 | TNBC | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 7830.017 | 0.8534 | 0.8244 | 1.7247 | |
| HCC1806 | TNBC | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 7830.017 | 0.8739 | 0.8496 | 1.7247 | |
| HCC1806 | TNBC | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 7830.017 | 0.6317 | 0.5323 | 1.7247 | |
| HCC1806 | TNBC | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 7830.017 | 0.4727 | 0.2953 | 1.7247 | |
| HCC1806 | TNBC | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 7830.017 | 0.3724 | 0.1280 | 1.7247 | |
| HCC1806 | TNBC | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 7830.017 | 0.2090 | -0.1930 | 1.7247 | |
| HCC1806 | TNBC | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 7830.017 | 0.1224 | -0.4084 | 1.7247 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 7832.017 | 0.9979 | 0.9969 | 1.3404 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 7832.017 | 0.9825 | 0.9739 | 1.3404 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 7832.017 | 1.0026 | 1.0038 | 1.3404 | |
| HCC1937 | TNBC | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 7832.017 | 0.9365 | 0.9045 | 1.3404 |