Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184A1 | NM | Basal | 5-FU | TYMS | TYMS | 19200 | uM | 9047.017 | 0.1196 | -0.8384 | 0.8440 | |
| 600MPE | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 9118.017 | 1.0015 | 1.0028 | 1.0401 | |
| 600MPE | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 9118.017 | 1.0269 | 1.0516 | 1.0401 | |
| 600MPE | HR+ | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 9118.017 | 0.9097 | 0.8261 | 1.0401 | |
| 600MPE | HR+ | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 9118.017 | 0.8801 | 0.7690 | 1.0401 | |
| 600MPE | HR+ | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 9118.017 | 0.8032 | 0.6201 | 1.0401 | |
| 600MPE | HR+ | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 9118.017 | 0.7039 | 0.4271 | 1.0401 | |
| 600MPE | HR+ | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 9118.017 | 0.2991 | -0.3733 | 1.0401 | |
| 600MPE | HR+ | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 9118.017 | 0.0465 | -0.8954 | 1.0401 | |
| 600MPE | HR+ | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 9118.017 | 0.0294 | -0.9327 | 1.0401 | |
| AU565 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 7793.035 | 1.0337 | 1.0554 | 1.2119 | |
| AU565 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 7793.035 | 0.8825 | 0.8040 | 1.2119 | |
| AU565 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 7793.035 | 0.7495 | 0.5765 | 1.2119 | |
| AU565 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 7793.035 | 0.7079 | 0.5040 | 1.2119 | |
| AU565 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 7793.035 | 0.6288 | 0.3639 | 1.2119 | |
| AU565 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 7793.035 | 0.4753 | 0.0827 | 1.2119 | |
| AU565 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 7793.035 | 0.3331 | -0.1925 | 1.2119 | |
| AU565 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 7793.035 | 0.2753 | -0.3101 | 1.2119 | |
| AU565 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 7793.035 | 0.2348 | -0.3950 | 1.2119 | |
| AU565 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 7794.017 | 1.0597 | 1.0593 | 1.9851 | |
| AU565 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 7794.017 | 1.0313 | 1.0313 | 1.9851 | |
| AU565 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 7794.017 | 0.8292 | 0.8199 | 1.9851 | |
| AU565 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 7794.017 | 0.5009 | 0.4119 | 1.9851 | |
| AU565 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 7794.017 | 0.5096 | 0.4241 | 1.9851 | |
| AU565 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 7794.017 | 0.5413 | 0.4681 | 1.9851 |