Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 9163.03 | 0.9137 | 0.5495 | 0.3535 | |
| BT-474 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 9163.03 | 0.7942 | 0.0422 | 0.3535 | |
| BT-474 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 9163.03 | 0.5519 | -0.6278 | 0.3535 | |
| BT-474 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 9163.03 | 0.3554 | -0.8928 | 0.3535 | |
| BT-474 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 9163.03 | 0.1214 | -0.9949 | 0.3535 | |
| BT-483 | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 7801.035 | 1.0285 | 1.1062 | 0.5427 | |
| BT-483 | HR+ | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 7801.035 | 0.9827 | 0.9367 | 0.5427 | |
| BT-483 | HR+ | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 7801.035 | 0.9951 | 0.9821 | 0.5427 | |
| BT-483 | HR+ | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 7801.035 | 0.9341 | 0.7640 | 0.5427 | |
| BT-483 | HR+ | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 7801.035 | 0.8293 | 0.4165 | 0.5427 | |
| BT-483 | HR+ | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 7801.035 | 0.7261 | 0.1089 | 0.5427 | |
| BT-483 | HR+ | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 7801.035 | 0.5638 | -0.3043 | 0.5427 | |
| BT-483 | HR+ | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 7801.035 | 0.3871 | -0.6521 | 0.5427 | |
| BT-483 | HR+ | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 7801.035 | 0.2651 | -0.8268 | 0.5427 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7803.017 | 0.9634 | 0.9749 | 2.9572 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7803.017 | 0.9643 | 0.9755 | 2.9572 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 1.23 | uM | 7803.017 | 0.9642 | 0.9755 | 2.9572 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 6.15 | uM | 7803.017 | 0.9148 | 0.9407 | 2.9572 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 30.7 | uM | 7803.017 | 0.6617 | 0.7393 | 2.9572 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 154 | uM | 7803.017 | 0.4473 | 0.5236 | 2.9572 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 769 | uM | 7803.017 | 0.3163 | 0.3551 | 2.9572 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 3840 | uM | 7803.017 | 0.2174 | 0.1939 | 2.9572 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 19200 | uM | 7803.017 | 0.1395 | 0.0274 | 2.9572 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.0492 | uM | 7804.017 | 0.9873 | 0.9902 | 2.5963 | |
| BT-549 | TNBC | Basal B | 5-FU | TYMS | TYMS | 0.246 | uM | 7804.017 | 0.9797 | 0.9843 | 2.5963 |