Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 7848.017 | 1.0665 | 1.4415 | 0.3225 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 7848.017 | 1.1114 | 1.7753 | 0.3225 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 7848.017 | 1.0558 | 1.3664 | 0.3225 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 7848.017 | 1.0695 | 1.4630 | 0.3225 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 7848.017 | 1.0614 | 1.4057 | 0.3225 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 7848.017 | 0.9955 | 0.9724 | 0.3225 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 7848.017 | 0.7581 | -0.1527 | 0.3225 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 7848.017 | 0.6164 | -0.5539 | 0.3225 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 7848.017 | 0.5065 | -0.7572 | 0.3225 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 7849.017 | 1.0484 | 1.2918 | 0.3471 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 7849.017 | 1.0850 | 1.5297 | 0.3471 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 1.23 | uM | 7849.017 | 1.0591 | 1.3597 | 0.3471 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 6.15 | uM | 7849.017 | 1.0486 | 1.2931 | 0.3471 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 30.7 | uM | 7849.017 | 1.0852 | 1.5316 | 0.3471 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 154 | uM | 7849.017 | 1.0151 | 1.0880 | 0.3471 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 769 | uM | 7849.017 | 0.7371 | -0.1695 | 0.3471 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 3840 | uM | 7849.017 | 0.6416 | -0.4431 | 0.3471 | |
| HCC2185 | TNBC | Luminal | 5-FU | TYMS | TYMS | 19200 | uM | 7849.017 | 0.5241 | -0.6891 | 0.3471 | |
| HCC3153 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 7853.017 | 0.9868 | 0.9848 | 1.7375 | |
| HCC3153 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 7853.017 | 0.9959 | 0.9953 | 1.7375 | |
| HCC3153 | TNBC | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 7853.017 | 0.9966 | 0.9961 | 1.7375 | |
| HCC3153 | TNBC | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 7853.017 | 0.9715 | 0.9669 | 1.7375 | |
| HCC3153 | TNBC | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 7853.017 | 0.9003 | 0.8827 | 1.7375 | |
| HCC3153 | TNBC | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 7853.017 | 0.7588 | 0.7063 | 1.7375 | |
| HCC3153 | TNBC | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 7853.017 | 0.5193 | 0.3716 | 1.7375 |