Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 33.3 | uM | 7860.016 | 0.6690 | 0.0398 | 0.6145 | |
| HCC70 | TNBC | Basal A | AG1478 | EGFR | ErbB | 167 | uM | 7860.016 | 0.0348 | -0.9915 | 0.6145 | |
| HMT-3522 S1 | Unknown | Unknown | AG1478 | EGFR | ErbB | 0.000427 | uM | 7911.016 | 1.0696 | 1.1037 | 1.3310 | |
| HMT-3522 S1 | Unknown | Unknown | AG1478 | EGFR | ErbB | 0.00213 | uM | 7911.016 | 0.9343 | 0.9005 | 1.3310 | |
| HMT-3522 S1 | Unknown | Unknown | AG1478 | EGFR | ErbB | 0.0107 | uM | 7911.016 | 1.0268 | 1.0401 | 1.3310 | |
| HMT-3522 S1 | Unknown | Unknown | AG1478 | EGFR | ErbB | 0.0533 | uM | 7911.016 | 0.7508 | 0.6125 | 1.3310 | |
| HMT-3522 S1 | Unknown | Unknown | AG1478 | EGFR | ErbB | 0.267 | uM | 7911.016 | 0.4161 | 0.0350 | 1.3310 | |
| HMT-3522 S1 | Unknown | Unknown | AG1478 | EGFR | ErbB | 1.33 | uM | 7911.016 | 0.4564 | 0.1095 | 1.3310 | |
| HMT-3522 S1 | Unknown | Unknown | AG1478 | EGFR | ErbB | 6.67 | uM | 7911.016 | 0.3957 | -0.0033 | 1.3310 | |
| HMT-3522 S1 | Unknown | Unknown | AG1478 | EGFR | ErbB | 33.3 | uM | 7911.016 | 0.3850 | -0.0237 | 1.3310 | |
| HMT-3522 S1 | Unknown | Unknown | AG1478 | EGFR | ErbB | 167 | uM | 7911.016 | 0.3994 | 0.0035 | 1.3310 | |
| Hs 578T | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 7861.016 | 0.9083 | 0.9082 | 2.0473 | |
| Hs 578T | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 7861.016 | 0.9458 | 0.9463 | 2.0473 | |
| Hs 578T | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 7861.016 | 0.9368 | 0.9373 | 2.0473 | |
| Hs 578T | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 7861.016 | 0.8616 | 0.8596 | 2.0473 | |
| Hs 578T | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 7861.016 | 0.9725 | 0.9729 | 2.0473 | |
| Hs 578T | TNBC | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 7861.016 | 0.8407 | 0.8374 | 2.0473 | |
| Hs 578T | TNBC | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 7861.016 | 0.7992 | 0.7926 | 2.0473 | |
| Hs 578T | TNBC | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 7861.016 | 0.7325 | 0.7179 | 2.0473 | |
| Hs 578T | TNBC | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 7861.016 | 0.3254 | 0.1558 | 2.0473 | |
| Hs 578T | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 7862.016 | 0.9813 | 0.9717 | 1.3229 | |
| Hs 578T | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 7862.016 | 1.0672 | 1.1008 | 1.3229 | |
| Hs 578T | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 7862.016 | 1.0501 | 1.0753 | 1.3229 | |
| Hs 578T | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 7862.016 | 1.0666 | 1.0999 | 1.3229 | |
| Hs 578T | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 7862.016 | 0.9904 | 0.9855 | 1.3229 |